Department of Gynecology and Obstetrics, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Department of Medical Imaging, Hematology, and Clinical Oncology, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Rev Bras Ginecol Obstet. 2020 Oct;42(10):672-675. doi: 10.1055/s-0040-1714721. Epub 2020 Oct 31.
Wernicke encephalopathy (WE) is an acute neurological disorder resulting from vitamin B1 deficiency, which is common in chronic alcoholism. We report a rare case of WE due to hyperemesis gravidarum in a 25-year-old pregnant patient at 13 weeks and 5 days of gestation. Initially, the disease manifested as weakness, mental confusion, anterograde amnesia, and visual and auditory hallucinations. The diagnosis was established after the detection of suggestive findings of WE in the thalamus by magnetic resonance imaging (MRI) and a rapid improvement in the patient's clinical status subsequent to treatment with thiamine. Hyperemesis is a rare cause of WE, which makes the reported case important in the literature and reinforces the need for attention in clinical practice to rare but important complications of this common condition (hyperemesis gravidarum).
威尼克脑病（WE）是一种由维生素 B1 缺乏引起的急性神经紊乱，常见于慢性酒精中毒。我们报告了一例罕见的威尼克脑病病例，患者为一名 25 岁的孕妇，妊娠 13 周零 5 天，因妊娠剧吐引起。最初，疾病表现为乏力、精神错乱、顺行性遗忘、视觉和听觉幻觉。经磁共振成像（MRI）检测到丘脑有威尼克脑病的提示性发现，并在给予硫胺素治疗后患者的临床状况迅速改善，从而做出了诊断。妊娠剧吐是威尼克脑病的罕见病因，该报道的病例在文献中具有重要意义，提示在临床实践中需要注意这种常见疾病（妊娠剧吐）的罕见但重要的并发症。
