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贝伐珠单抗治疗胃癌穿孔

Perforation of gastric metastasis during chemotherapy with ramucirumab.

机构信息

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Kita-ku, Okayama, Japan.

Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Kita-ku, Okayama, Japan.

出版信息

Curr Probl Cancer. 2021 Apr;45(2):100666. doi: 10.1016/j.currproblcancer.2020.100666. Epub 2020 Oct 22.

DOI:10.1016/j.currproblcancer.2020.100666
PMID:33129565
Abstract

A 59-year-old man received fifth line chemotherapy with ramucirumab and protein-bound paclitaxel for gastric metastasis from esophagogastric junction cancer. On day 3 of the third course, he had severe chest pain and a high fever. Esophagogastroduodenoscopy revealed gastric perforation at the point of the metastatic lesion.

摘要

一位 59 岁男性因胃食管结合部癌胃转移接受雷莫芦单抗联合白蛋白紫杉醇的五线化疗。在第三个疗程的第 3 天,他出现严重胸痛和高热。上消化道内镜检查显示转移病灶处胃穿孔。

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Perforation of gastric metastasis during chemotherapy with ramucirumab.贝伐珠单抗治疗胃癌穿孔
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Efficacy and safety of ramucirumab for gastric or gastro-esophageal junction adenocarcinoma: a systematic review and meta-analysis.雷莫芦单抗治疗胃或胃食管结合部腺癌的疗效和安全性:系统评价和荟萃分析。
Eur J Clin Pharmacol. 2024 Nov;80(11):1697-1714. doi: 10.1007/s00228-024-03734-1. Epub 2024 Aug 5.