Lin Yin, Wu Yi-Long, Zou Dong-Dong, Luo Xiao-Long, Zhang Shi-Yan
Department of Gastroenterology, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China.
Department of Proctology, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China.
World J Gastrointest Surg. 2024 Sep 27;16(9):3065-3073. doi: 10.4240/wjgs.v16.i9.3065.
Primary lung cancer is the leading cause of cancer-related death worldwide. Common metastatic sites include the brain, liver, bones, and adrenal glands. However, gastric metastases from lung cancer are rare. This case may be the first report of a combined gastroscopic and laparoscopic resection for gastric metastatic adenosquamous carcinoma (ASC).
We report a case of gastric metastasis from lung cancer. The patient was a 61-year-old Han Chinese female who first attended our hospital complaining of a persistent cough, leading to the diagnosis of advanced-stage lung adenocarcinoma. After more than four years of chemotherapy, the patient began to experience epigastric pain. Endoscopy was performed, and pathological examination of biopsy specimens confirmed that the gastric lesion was a metastasis from lung cancer. The lesion was successfully resected by combined gastroscopy and laparoscopy. Histopathological examination of the resected gastric specimen revealed ASC.
Gastric metastases from lung cancer are rare. Endoscopy, histological and immunohistochemical staining are useful for diagnosing metastatic lesions. Surgical management may provide extended survival in appropriately selected patients.
原发性肺癌是全球癌症相关死亡的主要原因。常见的转移部位包括脑、肝、骨和肾上腺。然而,肺癌的胃转移很少见。该病例可能是首例关于胃转移性腺鳞癌联合胃镜和腹腔镜切除术的报道。
我们报告一例肺癌胃转移病例。患者为一名61岁的汉族女性,最初因持续咳嗽就诊于我院,诊断为晚期肺腺癌。经过四年多的化疗后,患者开始出现上腹部疼痛。进行了内镜检查,活检标本的病理检查证实胃病变为肺癌转移。通过联合胃镜和腹腔镜成功切除了病变。切除的胃标本的组织病理学检查显示为腺鳞癌。
肺癌的胃转移很少见。内镜检查、组织学和免疫组化染色有助于诊断转移性病变。手术治疗可能为适当选择的患者延长生存期。