Kimura H, Nakagawa K, Sakaki S, Matsuoka K
Department of Neurosurgery, Ehime University School of Medicine, Japan.
No Shinkei Geka. 1987 Jun;15(6):663-8.
An 11-month-old male infant with intracranial meningioma is presented. Intracranial meningiomas in infancy under the age of 1 year are extremely rare, and only 22 cases have been reported previously. The authors reviewed the clinical and pathological findings of these meningiomas including our case. The patient feel ill with convulsive attacks followed by unconsciousness at 11 months of age without any other neurological deficit. Computed tomographic scannings revealed a high density lesion in the frontal region. The tumor was located entirely in the frontal lobe 2 cm anterior to the Sylvian vein and was removed en bloc. It was 3 X 3 X 3 cm in diameter and 10 g in weight. Histological diagnosis was of fibroblastic meningioma. He was discharged two weeks after the operation without any neurological deficits. Several characteristic features of meningiomas in infant under 1 year old were drawn from the review of literature in comparison with those of meningiomas in adult. 1) Predominant sex was male (16/23). 2) All meningiomas developed in the supra-tentorium. 3) Eight of 18 tumors being described did not have the dural attachment. 4) Nine of 16 tumors showed cyst formation. 5) The most cases were histologically diagnosed benign (17 of 22), and 15 cases was fibroblastic meningioma.
本文报告了一名患有颅内脑膜瘤的11个月大男婴。1岁以下婴儿的颅内脑膜瘤极为罕见，此前仅报道过22例。作者回顾了这些脑膜瘤（包括我们的病例）的临床和病理表现。该患者在11个月大时出现惊厥发作并随后昏迷，无任何其他神经功能缺损。计算机断层扫描显示额叶有一个高密度病变。肿瘤完全位于外侧裂静脉前方2 cm的额叶，整块切除。肿瘤直径为3×3×3 cm，重量为10 g。组织学诊断为纤维母细胞型脑膜瘤。术后两周出院，无任何神经功能缺损。通过文献回顾，总结了1岁以下婴儿脑膜瘤与成人脑膜瘤相比的几个特征：1）男性占优势（16/23）。2）所有脑膜瘤均发生于幕上。3）18例描述的肿瘤中有8例没有硬脑膜附着。4）16例肿瘤中有9例有囊肿形成。5）大多数病例组织学诊断为良性（22例中的17例），15例为纤维母细胞型脑膜瘤。
