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[2例囊性脑膜瘤]

[2 Cases of cystic meningioma].

作者信息

Imagawa K, Nomura T, Asai A, Hayashi M, Toda I, Kawasaki M, Yokoi K

出版信息

No Shinkei Geka. 1983 May;11(5):513-8.

PMID:6877510
Abstract

Although meningiomas are usually a solid and firm tumor, some are associated with diagnostically confusing large cysts. The authors experienced two cases of meningioma associated with large cyst (cystic meningioma). The first case was a 20-year-old female. She was admitted because of blurred vision. On admission she was slightly apathetic and showed bilateral papilledema. Computed tomography showed a large area of low density in both frontal regions. CT scan after intravenous contrast enhancement revealed an enhancing mural nodule attached to the falx. At operation, dark-green fluid in an amount of 160 ml from the left cyst and 50 ml from the right cyst was aspirated. The nodular tumor was found attached to the falx. The pathological examination revealed meningotheliomatous meningioma. Neoplastic meningothelial cells were found also in the cyst wall. The second case was a 21-year-old female. She was admitted because of weakness of the left lower extremity. Neurological examination revealed left hemiparesis. Deep tendon reflexes were hyperactive on the left side and there were positive left Babinski and Chaddock reflex. The computed tomography with contrast enhancement showed a large area of low density in the right parietal region with markedly enhancing mural nodule. At operation, 70 ml of xanthochromic fluid was aspirated. The tumor was well-defined, hard and attached to the dura. Histologically the tumor was a typical meningotheliomatous meningioma. The diagnostic value of computed tomography, the pathogenesis of cyst formation and the surgical treatment were discussed. The authors emphasized the important role of computed tomography in the diagnosis of cystic meningioma. Theories were reviewed for the pathogenesis of cyst formation. At operation, not only the mural nodule but also the cyst wall should be removed, because the neoplastic cells are presented in the cyst wall.

摘要

虽然脑膜瘤通常是实性且质地坚硬的肿瘤,但有些脑膜瘤伴有在诊断上容易造成混淆的大囊肿。作者遇到了两例与大囊肿相关的脑膜瘤(囊性脑膜瘤)。第一例是一名20岁女性。她因视力模糊入院。入院时她略显淡漠,双侧视乳头水肿。计算机断层扫描显示双侧额叶有大片低密度区。静脉注射造影剂增强后的CT扫描显示有一个强化的壁结节附着于大脑镰。手术时,从左侧囊肿抽出160毫升深绿色液体,从右侧囊肿抽出50毫升。发现结节状肿瘤附着于大脑镰。病理检查显示为脑膜皮型脑膜瘤。在囊肿壁上也发现了肿瘤性脑膜皮细胞。第二例是一名21岁女性。她因左下肢无力入院。神经系统检查显示左侧偏瘫。左侧深腱反射亢进,左侧巴宾斯基征和查多克征阳性。增强计算机断层扫描显示右侧顶叶有大片低密度区,有明显强化的壁结节。手术时,抽出70毫升淡黄色液体。肿瘤边界清晰、质地坚硬,附着于硬脑膜。组织学上,肿瘤是典型的脑膜皮型脑膜瘤。讨论了计算机断层扫描的诊断价值、囊肿形成的发病机制和手术治疗。作者强调了计算机断层扫描在囊性脑膜瘤诊断中的重要作用。回顾了囊肿形成发病机制的理论。手术时,不仅应切除壁结节,还应切除囊肿壁,因为囊肿壁中有肿瘤细胞。

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