Vadala Rohit, Princess Isabella
Metro Centre for Respiratory Diseases, Metro Multispeciality Hospital, Noida, Uttar Pradesh, India.
Department of Microbiology, Apollo Speciality Hospitals, Vanagaram Branch, Chennai, Tamil Nadu, India.
Indian J Crit Care Med. 2020 Sep;24(9):847-854. doi: 10.5005/jp-journals-10071-23557.
Maximum antibiotic usage within hospitals occurs in critical care areas. Reasons for this usage are the moribund state of patients, invasive devices, and protocol based necessity for empiric antibiotic initiation in most critical conditions. Although unavoidable, prudent use of antibiotics (empiric and therapeutic) should be tailored based on national or if available, unit-based hospital antibiogram. This forms the footstool of every antibiotic policy formulated at tertiary care hospitals. Strict adherence to antibiotic policy formulated based on hospital antibiogram largely benefits patients and hospital-wide antimicrobial stewardship is ensured. The necessity, benefits, key targets, and usefulness of antimicrobial stewardship program (AMSP) in critical care has been elaborated in this review. Vadala R, Princess I. Antimicrobial Stewardship Program in Critical Care-Need of the Hour. Indian J Crit Care Med 2020;24(9):847-854.
医院内抗生素使用量最大的情况发生在重症监护区域。出现这种使用情况的原因包括患者的濒死状态、侵入性设备,以及在大多数危急情况下基于方案进行经验性抗生素起始治疗的必要性。尽管不可避免,但应根据国家或(若有)基于单位的医院抗菌谱来审慎使用抗生素(经验性和治疗性)。这构成了三级护理医院制定的每项抗生素政策的基础。严格遵守基于医院抗菌谱制定的抗生素政策对患者大有裨益,并确保了全院范围的抗菌药物管理。本综述阐述了重症监护中抗菌药物管理计划(AMSP)的必要性、益处、关键目标和实用性。Vadala R,Princess I。《重症监护中的抗菌药物管理计划——当下之需》。《印度重症监护医学杂志》2020年;24(9):847 - 854。