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三级医院在大流行最初几个月对疑似或确诊的2019冠状病毒病感染且需要紧急手术干预的病例进行的观察性研究:病例系列

Observational study of the suspected or confirmed cases of sars COV-2 infection needing emergency surgical intervention during the first months of the pandemic in a third level hospital: Case series.

作者信息

González-Calatayud Dra Mariel, Vargas-Ábrego Dr Benito, Gutiérrez-Uvalle Dra Gabriela E, López-Romero Dra Sandra C, González-Pérez Dr Luis Gabriel, Carranco-Martínez Dr José Alberto, Raful-Zacarías-Ezzat Dr Jed, Gracida-Mancilla Dr Noé I

机构信息

Surgical Therapeutics Service of the Hospital General de México "Dr. Eduardo Liceaga", Mexico.

Thorax Surgery Service in Charge of Tracheotomies at the Hospital General de México "Dr. Eduardo Liceaga", Mexico.

出版信息

Ann Med Surg (Lond). 2020 Dec;60:149-154. doi: 10.1016/j.amsu.2020.10.038. Epub 2020 Oct 24.

Abstract

UNLABELLED

Approximately 28, 404, 603 surgical events have been suspended in the 12 peak weeks of the COVID-19 pandemic. The aim of this study was to report all the surgically intervened patients with suspected or confirmed SARS CoV-2 infection from April 1 to July 31, 2020, and to estimate their prognosis in the Surgical Therapy Department of a third level hospital in Mexico.

METHOD

We conducted an observational study of patients undergoing surgical intervention in the operating room assigned as COVID, where we considered age, sex, treating department, type of intervention, and initial biomarkers (first five days of hospitalization), days of hospital stay, days in the Intensive Care Unit and reason for discharge.

RESULTS

42 patients have been surgically intervened, with a total of 49 surgeries. For Otolaringology and General Surgery, there were more deceased cases than alive cases; while for Thoracic Surgery, and Obstetrics and Gynecology, there were more alive cases than deceased ones (36% and 0% deceased, respectively), with statistically significant differences ( = 0.014). With regard to mortality for each group of surgical procedure, patients who underwent C-section or pleurostomy had a mortality rate of 0%; the mortality rate for patients who underwent tracheostomy was 52%; patients who underwent laparotomy had a mortality rate of 54%; for those who underwent debridement, the mortality rate was 100%; which show significant differences, with a value of 0.03.

DISCUSSION

we identified an overall mortality rate of 42.8%, with a significant difference between treating departments and type of surgical procedure. This can be explained because many of the General Surgery patients, in addition to their infectious process by COVID-19, had another complication, like sepsis, In the same way, we can say that pregnant patients are healthy and have a physiological condition. Finally, patients undergoing an open tracheostomy had solely pulmonary complications.

CONCLUSION

There is no doubt that we face an unknown condition for which we have been learning tests along the way. This sample of cases undergoing surgery at the beginning of the COVID-19 pandemic can provide clues on relevant results that we must consider for future cases.

摘要

未标注

在新冠疫情的12个高峰周期间,约28404603例外科手术被暂停。本研究的目的是报告2020年4月1日至7月31日期间所有接受手术治疗的疑似或确诊感染新冠病毒的患者,并评估他们在墨西哥一家三级医院外科治疗科的预后情况。

方法

我们对在指定为新冠手术室接受手术干预的患者进行了一项观察性研究,我们考虑了年龄、性别、治疗科室、干预类型以及初始生物标志物(住院的前五天)、住院天数、重症监护病房天数和出院原因。

结果

42例患者接受了手术干预,共进行了49台手术。对于耳鼻喉科和普通外科,死亡病例多于存活病例;而对于胸外科以及妇产科,存活病例多于死亡病例(分别为36%和0%的死亡率),具有统计学显著差异(P = 0.014)。关于每组外科手术的死亡率,接受剖腹产或胸膜造口术的患者死亡率为0%;接受气管切开术的患者死亡率为52%;接受剖腹手术的患者死亡率为54%;接受清创术的患者死亡率为100%;这些显示出显著差异,P值为0.03。

讨论

我们确定总体死亡率为42.8%,治疗科室和外科手术类型之间存在显著差异。这可以解释为,许多普通外科患者除了感染新冠病毒外,还有其他并发症,如败血症。同样,我们可以说孕妇身体健康且处于生理状态。最后,接受开放式气管切开术的患者仅出现肺部并发症。

结论

毫无疑问,我们面临一种未知情况,在此过程中一直在摸索检验方法。这个在新冠疫情初期接受手术的病例样本可以为我们在未来病例中必须考虑的相关结果提供线索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9ba/7595937/ceb94d0335c7/gr1.jpg

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