Lei Chunling, Chen Li
Department of Ophthalmology, Xi'an No. 4 Hospital, Xi'an, Shannxi Province, China.
Department of Ophthalmology, Beijing ChaoYang Hospital, Capital Medical University, Beijing, China.
J Ophthalmol. 2020 Oct 20;2020:4819468. doi: 10.1155/2020/4819468. eCollection 2020.
The complex and uncertain prognosis of traumatic macular hole (TMH) makes it a difficult and challenging problem in clinical management. The features of spontaneously closed TMH and the time of vitrectomy remain unclear. This retrospective study aimed to demonstrate the optical coherence tomography (OCT) features of TMH, explore the relationship between OCT parameters and visual outcomes, and further evaluate the therapeutic effect of surgical management. Seventeen TMH patients were included in this study. 13 eyes of TMH received vitrectomy surgery and 4 eyes of TMH were closed spontaneously. Baseline patient characteristics, surgical details, and 6-month postoperative follow-up clinical assessment were recorded prospectively. There was a moderate rate (4/17 eyes, 23.5%) of spontaneous closure. The mean time of hole closure was 9.5 ± 9.9 weeks, and 75% occurred within three months. In the spontaneously closed TMH eyes ( = 4), an intact ellipsoid band was observed in all four patients with a mean age of 12.0 ± 1.6 years and a smaller preoperative basal diameter of 418.0 ± 283.6 m. Small basal diameter of the macular hole at baseline ( = 0.02) was associated with spontaneous closure of TMH acuity. In the vitrectomy surgery group ( = 13), an intact ellipsoid band was observed in four patients (4/13) with a mean age of 27.0 ± 12.7 years and a larger preoperative basal diameter of 943.0 ± 444.2 m ( = 0.02). Vitrectomy results in a better closure rate (11/13 eyes, 84.6%). Combined with the spontaneously closed TMH eyes, the overall hole closure rate was 88.2% (15/17 eyes). After 6-month treatment for all patients, the best-corrected visual acuity (BCVA) increased to 0.59 ± 0.40 (logMAR) compared to baseline 1.01 ± 0.50 (logMAR) ( < 0.001). The ellipsoid band integrity was found to be closely correlated with visual acuity ( = 0.03). In conclusion, vitrectomy is an effective treatment for TMH. Surgical management for TMH achieved better anatomical closure and improved visual outcomes. Observation for 3 months may be considered before deciding if surgical intervention is suitable.
创伤性黄斑裂孔(TMH)复杂且不确定的预后使其成为临床治疗中一个困难且具有挑战性的问题。TMH自发闭合的特征以及玻璃体切除术的时机仍不明确。这项回顾性研究旨在展示TMH的光学相干断层扫描(OCT)特征,探索OCT参数与视觉结果之间的关系,并进一步评估手术治疗的效果。本研究纳入了17例TMH患者。13只TMH眼接受了玻璃体切除手术,4只TMH眼自发闭合。前瞻性记录了患者的基线特征、手术细节以及术后6个月的随访临床评估情况。自发闭合率为中等水平(4/17眼,23.5%)。裂孔闭合的平均时间为9.5±9.9周,75%的闭合发生在三个月内。在自发闭合的TMH眼中(n = 4),所有4例患者均观察到完整的椭圆体带,平均年龄为12.0±1.6岁,术前基底直径较小,为418.0±283.6μm。黄斑裂孔基线时较小的基底直径(P = 0.02)与TMH视力的自发闭合相关。在玻璃体切除手术组(n = 13)中,4例患者(4/13)观察到完整的椭圆体带,平均年龄为27.0±12.7岁,术前基底直径较大,为943.0±444.2μm(P = 0.02)。玻璃体切除术的闭合率更高(11/13眼,84.6%)。结合自发闭合眼,总体裂孔闭合率为88.2%(15/17眼)。所有患者经过6个月治疗后,最佳矫正视力(BCVA)从基线时的1.01±0.50(logMAR)提高到0.59±0.40(logMAR)(P < 0.001)。发现椭圆体带的完整性与视力密切相关(P = 0.03)。总之,玻璃体切除术是治疗TMH的有效方法。TMH的手术治疗实现了更好的解剖学闭合并改善了视觉结果。在决定是否适合进行手术干预之前,可考虑观察3个月。