Ito Hiroshi
Hospital Medicine, University of Tsukuba Hospital, Tsukuba, JPN.
Cureus. 2020 Sep 28;12(9):e10698. doi: 10.7759/cureus.10698.
Water intoxication often causes hyponatremia. Acute hyponatremia and its rapid correction have been reported to cause rhabdomyolysis. However, little is known about the clinical course of water-intoxication-related rhabdomyolysis. We report a case of self-induced water intoxication resulting in rhabdomyolysis, in which serum creatinine kinase surged rapidly. The appropriate selection of fluid therapy was difficult because of the differences in the standard treatments for each complication. Water restriction is used to treat water intoxication, while the opposite, fluid resuscitation, is used to treat rhabdomyolysis. Close monitoring of serum creatinine kinase was useful in determining fluid management in such a situation.
水中毒常导致低钠血症。据报道，急性低钠血症及其快速纠正可导致横纹肌溶解。然而，关于与水中毒相关的横纹肌溶解的临床病程知之甚少。我们报告了一例因自我诱导的水中毒导致横纹肌溶解的病例，其中血清肌酸激酶迅速飙升。由于每种并发症的标准治疗方法不同，因此难以选择合适的液体疗法。限制水分摄入用于治疗水中毒，而相反，液体复苏则用于治疗横纹肌溶解。密切监测血清肌酸激酶有助于确定这种情况下的液体管理。
