Low Carissa A
Department of Medicine, University of Pittsburgh, 3347 Forbes Avenue, Suite 200, Pittsburgh, PA 15213 USA.
NPJ Digit Med. 2020 Oct 27;3:140. doi: 10.1038/s41746-020-00351-x. eCollection 2020.
As smartphones and consumer wearable devices become more ubiquitous, there is a growing opportunity to capture rich mobile sensor data continuously, passively, and in real-world settings with minimal burden. In the context of cancer, changes in these passively sensed digital biomarkers may reflect meaningful variation in functional status, symptom burden, quality of life, and risk for adverse clinical outcomes. These data could enable real-time remote monitoring of patients between clinical encounters and more proactive, comprehensive, and personalized care. Over the past few years, small studies across a variety of cancer populations support the feasibility and potential clinical value of mobile sensors in oncology. Barriers to implementing mobile sensing in clinical oncology care include the challenges of managing and making sense of continuous sensor data, patient engagement issues, difficulty integrating sensor data into existing electronic health systems and clinical workflows, and ethical and privacy concerns. Multidisciplinary collaboration is needed to develop mobile sensing frameworks that overcome these barriers and that can be implemented at large-scale for remote monitoring of deteriorating health during or after cancer treatment or for promotion and tailoring of lifestyle or symptom management interventions. Leveraging digital technology has the potential to enrich scientific understanding of how cancer and its treatment affect patient lives, to use this understanding to offer more timely and personalized support to patients, and to improve clinical oncology outcomes.
随着智能手机和消费级可穿戴设备越来越普及，以最小负担在现实环境中持续、被动地获取丰富的移动传感器数据的机会也在增加。在癌症领域，这些被动感知的数字生物标志物的变化可能反映出功能状态、症状负担、生活质量以及不良临床结局风险方面的有意义变化。这些数据能够实现临床就诊期间患者的实时远程监测以及更积极、全面和个性化的护理。在过去几年中，针对各类癌症人群开展的小型研究支持了移动传感器在肿瘤学中的可行性和潜在临床价值。在临床肿瘤护理中实施移动传感面临的障碍包括管理和理解连续传感器数据的挑战、患者参与问题、将传感器数据整合到现有电子健康系统和临床工作流程的困难以及伦理和隐私问题。需要多学科合作来开发移动传感框架，以克服这些障碍，并能够大规模实施，用于远程监测癌症治疗期间或之后健康状况的恶化，或用于促进和定制生活方式或症状管理干预措施。利用数字技术有潜力丰富对癌症及其治疗如何影响患者生活的科学理解，利用这一理解为患者提供更及时和个性化的支持，并改善临床肿瘤学结局。
