甲醇中毒预后的相关因素；一项为期8年的回顾性横断面研究。
Prognostic Factors of Outcome in Methanol Poisoning; an 8-year Retrospective Cross-sectional Study.
作者信息
Yousefinejad Vahid, Moradi Badia, Mohammadi Baneh Anvar, Sheikhesmaeili Farshad, Babahajian Asrin
机构信息
Liver and Digestive Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
出版信息
Arch Acad Emerg Med. 2020 Sep 5;8(1):e69. eCollection 2020.
INTRODUCTION
Identification of high-risk patients with poor prognosis is essential for quick diagnosis and treatment of methanol poisoning to prevent death and improve the outcome. The aim of this study was to evaluate the clinical and laboratory factors in patients with methanol poisoning to determine the prognosis and outcome.
METHODS
In this retrospective cross-sectional study, all patients with methanol poisoning, who had presented to the emergency department of Tohid Hospital, Sanandaj, Iran from 2011 to 2019 (8 years) were enrolled using census method. Multivariate logistic regression analysis was performed to find the independent predictive factors of poor outcome in the mentioned patients.
RESULT
Methanol poisoning was diagnosed in 52 (11.55%) of the 450 cases admitted to hospital for alcohol intoxication. In multivariate analysis, time interval from methanol intake to hospital admission (OR=1.06; 95% CI= 1.00-1.11; p=0.04), respiratory arrest (OR=25.59; 95% CI= 1.37-478.13; p=0.03), and higher concentration of blood glucose (OR=1.03; 95% CI= 1.00-1.09; p=0.03) had a significant correlation with Poor outcomes.
CONCLUSIONS
Based on the findings of this study, delayed admission to hospital, respiratory arrest and were identified as independent risk factors of poor outcome in
引言
识别预后不良的高危患者对于甲醇中毒的快速诊断和治疗至关重要，以预防死亡并改善预后。本研究的目的是评估甲醇中毒患者的临床和实验室因素，以确定预后和结局。
方法
在这项回顾性横断面研究中，采用普查方法纳入了2011年至2019年（8年）期间在伊朗萨南达季托希德医院急诊科就诊的所有甲醇中毒患者。进行多因素逻辑回归分析，以找出上述患者预后不良的独立预测因素。
结果
在因酒精中毒入院的450例患者中，有52例（11.55%）被诊断为甲醇中毒。在多因素分析中，从摄入甲醇到入院的时间间隔（OR=1.06；95%CI=1.00-1.11；p=0.04）、呼吸骤停（OR=25.59；95%CI=1.37-478.13；p=0.03）和血糖浓度升高（OR=1.03；95%CI=1.00-1.09；p=0.03）与不良结局显著相关。
结论
基于本研究的结果，入院延迟、呼吸骤停被确定为……不良结局的独立危险因素
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