Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.
Org Biomol Chem. 2020 Nov 28;18(44):8994-9017. doi: 10.1039/d0ob01874k. Epub 2020 Nov 2.
The development of versatile and mild methodologies for C-N bond construction has always been a hot topic of interest in synthetic organic chemistry. In recent years, electrochemistry has emerged as a promising green and sustainable environmentally benign approach to carry out these transformations under mild conditions utilizing electrons as oxidizing/reducing agents. The current state-of-the-art in combining electrocatalysis with transition metal catalysis has gained significant attention. This hybrid synthetic methodology has increasingly become a common tool and offers many potential advantages compared to direct electrolysis. This review comprehensively highlights recent developments in the merging of transition metal catalysis in electro-organic synthesis for the facile construction of C-N bonds. In this review major emphasis is given to mechanistic investigations and their synthetic applications of this hybrid catalysis.
用于 C-N 键构建的多功能和温和方法的发展一直是合成有机化学中感兴趣的热门话题。近年来，电化学作为一种很有前途的绿色和可持续的环保方法，利用电子作为氧化剂/还原剂，在温和条件下进行这些转化，已经引起了人们的关注。将电催化与过渡金属催化相结合的最新进展引起了人们的高度关注。与直接电解相比，这种混合合成方法已逐渐成为一种常用的工具，并具有许多潜在的优势。本综述全面介绍了电有机合成中过渡金属催化融合用于 C-N 键简便构建的最新进展。本综述主要侧重于该混合催化的机理研究及其在合成中的应用。
