Department of Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
Orthopaedic Surgery, South West London Elective Orthopaedic Centre, Epsom, UK.
Bone Joint J. 2020 Nov;102-B(11):1519-1526. doi: 10.1302/0301-620X.102B11.BJJ-2019-1327.R1.
The primary aim of this study was to assess whether the postoperative Oxford Knee Score (OKS) demonstrated a ceiling effect at one and/or two years after total knee arthroplasty (TKA). The secondary aim was to identify preoperative independent predictors for patients that achieved a ceiling score after TKA.
A retrospective cohort of 5,857 patients undergoing a primary TKA were identified from an established arthroplasty database. Patient demographics, body mass index (BMI), OKS, and EuroQoL five-dimension (EQ-5D) general health scores were collected preoperatively and at one and two years postoperatively. Logistic regression analysis was used to identify independent preoperative predictors of patients achieving postoperative ceiling scores. Receiver operating characteristic curve was used to identify a preoperative OKS that predicted a postoperative ceiling score.
The ceiling effect was 4.6% (n = 272) at one year which increased significantly (odds ratio (OR) 40.3, 95% confidence interval (CI) 30.4 to 53.3; p < 0.001) to 6.2% (n = 363) at two years, when defined as those with a maximal score of 48 points. However, when the ceiling effect was defined as an OKS of 44 points or more, this increased to 26.3% (n = 1,540) at one year and further to 29.8% (n = 1,748) at two years (OR 21.6, 95% CI 18.7 to 25.1; p < 0.001). A preoperative OKS of 23 or more and 22 or more were predictive of achieving a postoperative ceiling OKS at one and two years when defined as a maximal score or a score of 44 or more, respectively.
The postoperative OKS demonstrated a small ceiling effect when defined by a maximal score, but when defined by a postoperative OKS of 44 or more the ceiling effect was moderate and failed to meet standards. The preoperative OKS was an independent predictor of achieving a ceiling score. Cite this article: 2020;102-B(11):1519-1526.
本研究的主要目的是评估全膝关节置换术(TKA)后 1 年和/或 2 年,术后牛津膝关节评分(OKS)是否存在天花板效应。次要目的是确定 TKA 后达到天花板评分的患者的术前独立预测因素。
从一个已建立的关节置换数据库中确定了 5857 名接受初次 TKA 的患者的回顾性队列。收集患者的人口统计学、体重指数(BMI)、OKS 和欧洲五维健康量表(EQ-5D)一般健康评分,分别在术前和术后 1 年和 2 年进行。使用逻辑回归分析确定达到术后天花板评分的患者的术前独立预测因素。使用受试者工作特征曲线来确定预测术后天花板评分的术前 OKS。
一年时的天花板效应为 4.6%(n=272),显著增加(比值比(OR)40.3,95%置信区间(CI)30.4 至 53.3;p<0.001)至两年时的 6.2%(n=363),此时定义为最大得分为 48 分的患者。然而,当天花板效应定义为 OKS 得分为 44 分或更高时,一年时增加到 26.3%(n=1540),两年时进一步增加到 29.8%(n=1748)(OR 21.6,95%CI 18.7 至 25.1;p<0.001)。术前 OKS 为 23 或更高和 22 或更高时,分别定义为术后最大 OKS 或 44 或更高的 OKS 评分时,预测达到术后天花板 OKS。
当定义为最大评分时,术后 OKS 表现出较小的天花板效应,但当定义为术后 OKS 为 44 或更高时,天花板效应中等,且未达到标准。术前 OKS 是达到天花板评分的独立预测因素。
文献来源:Lawrence NJ, Pandit H, Beard DJ, et al. The postoperative Oxford Knee Score demonstrates a ceiling effect at one and two years after total knee arthroplasty. Bone Joint J 2020;102-B(11):1519-1526.