Groden G, Groden J, Dondey M, Zane T, Pueschel S M, Veliceur W
Behavioral Development Center, Rhode Island.
Res Dev Disabil. 1987;8(2):203-11. doi: 10.1016/0891-4222(87)90004-7.
The present report, part of a national, multicenter study to investigate the effects of fenfluramine on autistic behavior, describes findings on four autistic children ranging in age from 7 to 20 years. Additional performance and parental observation measures apart from those of the multicenter study are included. Results of this study which indicated no significant side effects, a reduction in some deviant behaviors and an improvement in activity level/attention span, provide support for earlier reports. The possibility that fenfluramine's apparently positive effects might be to simply reduce inappropriate behaviors via lethargy was examined and not supported.
