Department of Chemistry, Indian Institute of Technology Guwahati, North Guwahati, Kamrup, Assam, 781039, India.
Present address: Department of Chemistry, Ben-Gurion University of Negev, Beer Sheva, 84105, Israel.
Chem Asian J. 2020 Dec 14;15(24):4291-4296. doi: 10.1002/asia.202001184. Epub 2020 Nov 17.
Widespread use of picric acid (PA) in chemical industries and deadly explosives poses dreadful impact on all living creatures as well as the natural environment and has raised global concerns that necessitate the development of fast and efficient sensing platforms. To address this issue, herein, we report a perylenediimide-peptide conjugate, PDI-1, for detection of PA in methanol. The probe displays typical aggregation caused quenching (ACQ) behaviour and exhibits a fluorescence "turn-off" sensory response towards PA which is unaffected by the presence of other interfering nitroaromatic compounds. The sensing mechanism involves PA induced aggregation of the probe into higher order tape like structures which leads to quenching of emission. The probe possesses a low detection limit of 5.6 nM or 1.28 ppb and a significantly high Stern-Volmer constant of 6.87×10 M . It also exhibits conducting properties in the presence of PA vapours and thus represents a prospective candidate for vapour phase detection of PA. This is, to the best of our knowledge, the first example of a perylenediimide based probe that demonstrates extremely specific, selective and sensitive detection of PA and thus grasps the potential for application in practical scenarios.
广泛应用于化学工业和致命炸药的苦味酸（PA）对所有生物以及自然环境都造成了可怕的影响，引起了全球关注，这就需要开发快速高效的传感平台。针对这一问题，本研究报告了一种苝二酰亚胺-肽缀合物 PDI-1，用于甲醇中 PA 的检测。该探针表现出典型的聚集诱导猝灭（ACQ）行为，并对 PA 表现出荧光“关闭”的传感响应，不受其他干扰的硝基芳烃化合物的影响。传感机制涉及 PA 诱导探针聚集为更高阶的带状结构，导致发射猝灭。该探针的检测限低至 5.6 nM 或 1.28 ppb，斯托克夫尔常数非常高，为 6.87×10 M 。它在 PA 蒸气存在下也表现出导电性，因此是气相 PA 检测的有前途的候选物。据我们所知，这是首例基于苝二酰亚胺的探针，对 PA 具有极高的特异性、选择性和灵敏性检测，因此有望在实际应用中得到应用。
