Nagoev B S, Gabrilovich I M
Ter Arkh. 1987;59(7):57-61.
A study of the functional-metabolic activity of neutrophilic leukocytes was performed in 54 patients with salmonellosis using cytochemical and luminescent-cytofluorimetric methods. The time course of disease revealed regular changes of the most important components of the leukocytic microbicidal system and indices of the NBT test activity depending on a stage, degree of severity, clinical type and type of applied therapy. Profound quantitative and qualitative shifts of the intraleukocytic components of the microbicidal system and indices of the NBT test of neutrophilic granulocytes in the time course of salmonellosis characterized the state of nonspecific body resistance.
采用细胞化学和发光细胞荧光测定法,对54例沙门氏菌病患者的嗜中性白细胞功能代谢活性进行了研究。疾病的病程显示,白细胞杀菌系统最重要组成部分以及硝基四氮唑蓝(NBT)试验活性指标会根据疾病阶段、严重程度、临床类型及所采用的治疗方法发生规律性变化。在沙门氏菌病病程中,杀菌系统白细胞内成分以及嗜中性粒细胞NBT试验指标发生的深度定量和定性变化,表征了机体非特异性抵抗力的状态。