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[沙门氏菌病病程中体液免疫指标及补体功能活性]

[The humoral immunity indices and complement functional activity in salmonellosis during the dynamics of the disease].

作者信息

Kulikova I N, Kasimova N B, Sazhnev S V, Karpenko S F, Arshba T E, Gor'kova A I

出版信息

Ter Arkh. 1996;68(4):75-7.

PMID:9324802
Abstract

In 65 patients with bacteriologically confirmed gastrointestinal salmonellosis of moderate severity (41 males and 24 females) the disease in an acute phase was characterized by activation of complement system and specific antibody formation, by a growth in the levels of IgA, G and M. In early convalescence IgA and IgM remained high, IgG in females returned to normal, in males was still high. An inverse correlation was found between functional activity of complement components C3, C4 and C5 and levels of IgM, IgG.

摘要

在65例经细菌学确诊为中度严重程度胃肠道沙门氏菌病的患者中(41例男性,24例女性),急性期疾病的特征为补体系统激活和特异性抗体形成,IgA、G和M水平升高。在恢复期早期,IgA和IgM仍保持较高水平,女性的IgG恢复正常,男性的IgG仍较高。发现补体成分C3、C4和C5的功能活性与IgM、IgG水平呈负相关。

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