Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Stoke-on-Trent, United Kingdom (C.S.K., M.A.M.).
Department of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom (C.S.K., M.A.M.).
Circ Cardiovasc Interv. 2020 Nov;13(11):e009654. doi: 10.1161/CIRCINTERVENTIONS.120.009654. Epub 2020 Nov 3.
The objective of the study was to evaluate changes in percutaneous coronary intervention (PCI) practice in England by analyzing procedural numbers, changes in the clinical presentation, and characteristics of patients and their clinical outcomes during the coronavirus disease 2019 (COVID-19) pandemic.
We conducted a retrospective cohort study of all patients who underwent PCI in England between January 2017 and April 2020 in the British Cardiovascular Intervention Society database.
Forty-four hospitals reported PCI procedures for 126 491 patients. There were ≈700 procedures performed each week before the lockdown. After the March 23, 2020 lockdown (11th/12th week in 2020), there was a 49% fall in the number of PCI procedures after the 12th week in 2020. The decrease was greatest in PCI procedures performed for stable angina (66%), followed by non-ST-segment-elevation myocardial infarction (45%), and ST-segment-elevation myocardial infarction (33%). Patients after the lockdown were younger (64.5 versus 65.5 years, <0.001) and less likely to have diabetes (20.4% versus 24.6%, <0.001), hypertension (52.0% versus 56.8%, =0.001), previous myocardial infarction (23.5% versus 26.7%, =0.008), previous PCI (24.3% versus 28.3%, =0.001), or previous coronary artery bypass graft (4.6% versus 7.2%, <0.001) compared with before the lockdown.
The lockdown in England has resulted in a significant decline in PCI procedures. Fewer patients underwent PCI for stable angina. This enabled greater capacity for urgent and emergency cases, and a reduced length of stay was seen for such patients. Significant changes in the characteristics of patients towards a lower risk phenotype were observed, particularly for non-ST-segment-elevation myocardial infarction, reflecting a more conservative approach to this cohort.
本研究旨在通过分析手术数量、临床表现变化以及患者特征及其临床结局,评估英格兰经皮冠状动脉介入治疗(PCI)实践的变化。
我们对英国心血管介入学会数据库中 2017 年 1 月至 2020 年 4 月期间在英格兰接受 PCI 的所有患者进行了回顾性队列研究。
44 家医院报告了 126491 例患者的 PCI 手术。封锁前每周约有 700 例手术。2020 年 3 月 23 日(第 11/12 周)封锁后,2020 年第 12 周后 PCI 手术数量下降了 49%。稳定型心绞痛的 PCI 手术减少最多(66%),其次是非 ST 段抬高型心肌梗死(45%)和 ST 段抬高型心肌梗死(33%)。封锁后的患者年龄更小(64.5 岁比 65.5 岁,<0.001),且更年轻糖尿病(20.4%比 24.6%,<0.001)、高血压(52.0%比 56.8%,=0.001)、既往心肌梗死(23.5%比 26.7%,=0.008)、既往 PCI(24.3%比 28.3%,=0.001)或既往冠状动脉旁路移植术(4.6%比 7.2%,<0.001)。
英格兰的封锁导致 PCI 手术数量显著下降。接受稳定型心绞痛 PCI 的患者减少。这为紧急和紧急情况下提供了更大的容量,并减少了此类患者的住院时间。观察到患者特征朝着低风险表型发生了重大变化,尤其是非 ST 段抬高型心肌梗死,反映了对这一组患者更为保守的方法。