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西班牙 COVID-19 大流行期间糖尿病患者心脏介入治疗的应用:对院内死亡率的影响。

Use of Cardiac Procedures in People with Diabetes during the COVID Pandemic in Spain: Effects on the In-Hospital Mortality.

机构信息

Department of Public Health & Maternal and Child Health, Faculty of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain.

Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain.

出版信息

Int J Environ Res Public Health. 2023 Jan 2;20(1):844. doi: 10.3390/ijerph20010844.

Abstract

We aimed to assess the effect of the COVID-19 pandemic in Spain on people with diabetes undergoing cardiac procedures, such as coronary artery bypass graft (CABG), percutaneous coronary intervention (PCI), open surgical valve replacement (OSVR), and transcatheter valve implantation (TCVI). We compared the year 2019 with the year 2020. We conducted an observational study using data from the Spanish National Hospital Discharge Database from 1 January 2019 to 31 December 2020. In 2020, a total of 21,067 cardiac procedures were performed on people with diabetes compared with 24,675 in the previous year. The use of CABG, PCI, OSVR and TCVI decreased from 2019 to 2020 by 13.9%, 14.8%, 21.4% and 2.9%, respectively. In 2020, patients had a significantly higher mean Charlson Comorbidity Index than in 2019 for all the cardiac procedures analyzed. In-hospital mortality (IHM) was higher ( > 0.05) for all the procedures in the year 2020. Over the entire period, female sex was a significant risk factor for IHM among those who underwent CABG, PCI and OSVR (OR 1.94, 95%CI 1.41-2.66; OR 1.19, 95%CI 1.05-1.35; and OR 1.79, 95%CI 1.38-2.32, respectively). The sensitivity analysis including two more years, 2017 and 2018, confirmed that female patients and comorbidity were risk factors for IHM in patients with diabetes regardless of whether it was during the pandemic era or before. We conclude that the frequency of cardiac procedures among people with diabetes declined in 2020. IHM did not change significantly in the COVID-19 era.

摘要

我们旨在评估西班牙 COVID-19 大流行对接受心脏手术的糖尿病患者的影响,如冠状动脉旁路移植术(CABG)、经皮冠状动脉介入治疗(PCI)、开放式心脏瓣膜置换术(OSVR)和经导管心脏瓣膜植入术(TCVI)。我们将 2019 年与 2020 年进行了比较。我们使用了 2019 年 1 月 1 日至 2020 年 12 月 31 日期间来自西班牙国家住院数据库的数据进行了一项观察性研究。2020 年,共有 21067 例糖尿病患者接受了心脏手术,而前一年为 24675 例。CABG、PCI、OSVR 和 TCVI 的使用率分别从 2019 年下降至 2020 年的 13.9%、14.8%、21.4%和 2.9%。2020 年,与 2019 年相比,所有分析的心脏手术患者的平均 Charlson 合并症指数均显著升高。2020 年,所有手术的院内死亡率(IHM)均较高(>0.05)。在整个研究期间,女性是接受 CABG、PCI 和 OSVR 手术的患者发生 IHM 的显著危险因素(OR 1.94,95%CI 1.41-2.66;OR 1.19,95%CI 1.05-1.35;OR 1.79,95%CI 1.38-2.32)。包括 2017 年和 2018 年在内的敏感性分析证实,无论是否处于大流行时期,女性患者和合并症均是糖尿病患者 IHM 的危险因素。我们得出结论,2020 年糖尿病患者心脏手术的频率下降。在 COVID-19 时代,IHM 并未显著改变。

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