Advocate Children's Hospital, Chicago, IL, USA.
Chicago Medical School, Rosalind Franklin University of Medicine and Science, Chicago, IL, USA.
Ann Med. 2021 Dec;53(1):151-159. doi: 10.1080/07853890.2020.1840620.
To utilize publicly reported, state-level data to identify factors associated with the frequency of cases, tests, and mortality in the USA.
Retrospective study using publicly reported data collected included the number of COVID-19 cases, tests and mortality from March 14th through April 30th. Publicly available state-level data was collected which included: demographics comorbidities, state characteristics and environmental factors. Univariate and multivariate regression analyses were performed to identify the significantly associated factors with percent mortality, case and testing frequency. All analyses were state-level analyses and not patient-level analyses.
A total of 1,090,500 COVID-19 cases were reported during the study period. The calculated case and testing frequency were 3332 and 19,193 per 1,000,000 patients. There were 63,642 deaths during this period which resulted in a mortality of 5.8%. Factors including to but not limited to population density (beta coefficient 7.5, < .01), transportation volume (beta coefficient 0.1, < .01), tourism index (beta coefficient -0.1, = .02) and older age (beta coefficient 0.2, = .01) are associated with case frequency and percent mortality.
There were wide variations in testing and case frequencies of COVID-19 among different states in the US. States with higher population density had a higher case and testing rate. States with larger population of elderly and higher tourism had a higher mortality. Key messages There were wide variations in testing and case frequencies of COVID-19 among different states in the USA. States with higher population density had a higher case and testing rate. States with larger population of elderly and higher tourism had a higher mortality.
利用公开报告的州级数据,确定与美国 COVID-19 病例、检测和死亡率频率相关的因素。
本研究采用回顾性研究设计,使用公开报告的数据,包括 3 月 14 日至 4 月 30 日期间的 COVID-19 病例、检测和死亡率。收集了公开的州级数据,包括人口统计学特征、合并症、州特征和环境因素。采用单变量和多变量回归分析,确定与死亡率、病例和检测频率百分比显著相关的因素。所有分析均为州级分析,而非患者级分析。
研究期间共报告了 1090500 例 COVID-19 病例。计算得出的病例和检测频率分别为每 100 万人中 3332 例和 19193 例。在此期间有 63642 人死亡,死亡率为 5.8%。人口密度(β系数 7.5, < 0.01)、交通量(β系数 0.1, < 0.01)、旅游指数(β系数-0.1, = 0.02)和年龄较大(β系数 0.2, = 0.01)等因素与病例频率和死亡率百分比有关。
美国不同州 COVID-19 的检测和病例频率存在广泛差异。人口密度较高的州病例和检测率较高。老年人口和旅游人数较多的州死亡率较高。
美国不同州 COVID-19 的检测和病例频率存在广泛差异。人口密度较高的州病例和检测率较高。老年人口和旅游人数较多的州死亡率较高。