Department of Psychiatry and Psychotherapy, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Transl Psychiatry. 2020 Nov 2;10(1):371. doi: 10.1038/s41398-020-01062-3.
Early life stress is an important factor in later psychopathology, including symptoms of posttraumatic stress disorder (PTSD), depression, and anxiety. The purpose of the present study was to investigate the effect of early life stress on psychiatric symptoms within a sample of Syrian refugees. In this model, the use of cognitive emotion regulation strategies was assessed as a potential mediator of the relationship between early life stress and current symptoms of PTSD, depression, and anxiety. Bootstrap analyses were generated to test the indirect effect of emotion regulation (Cognitive Emotion Regulation Questionnaire) on the relationship between early life stress (Childhood Trauma Questionnaire), PTSD (Harvard Trauma Questionnaire), depressive (PHQ-9) and anxiety (GAD-7) symptoms in eighty-nine Syrian refugees resided in Germany (n = 49) and Jordan (n = 40). The indirect effect of maladaptive strategies was significant between early life stress and psychopathology, whereas the mediation effect of adaptive strategies was not significant. The findings provide an evidence that emotional dysregulation is an underlying factor affecting psychological symptoms in refugees with adverse childhood experiences. These results suggest targeting cognitive emotion regulation in prospective prevention and treatment strategies.
早期生活压力是后期精神病理学的一个重要因素，包括创伤后应激障碍（PTSD）、抑郁和焦虑的症状。本研究的目的是在叙利亚难民样本中调查早期生活压力对精神症状的影响。在该模型中，使用认知情绪调节策略来评估其作为早期生活压力与当前 PTSD、抑郁和焦虑症状之间关系的潜在中介。采用 Bootstrap 分析来检验情绪调节（认知情绪调节问卷）对早期生活压力（儿童期创伤问卷）、PTSD（哈佛创伤问卷）、抑郁（PHQ-9）和焦虑（GAD-7）症状之间关系的间接影响，这些症状在居住在德国（n=49）和约旦（n=40）的 89 名叙利亚难民中进行了评估。不良策略的间接效应在早期生活压力和精神病理学之间具有统计学意义，而适应性策略的中介效应则不具有统计学意义。这些发现为情绪失调是影响经历过不良童年经历的难民心理症状的一个潜在因素提供了证据。这些结果表明，在未来的预防和治疗策略中应针对认知情绪调节。
