Hoffmann Institute of Advanced Materials, Shenzhen Polytechnic, 7098 Liuxian Boulevard, Shenzhen, Guangdong, 518055, P. R. China.
Department of Chemistry and Chemical Biology, Rutgers University, 123 Bevier Road, Piscataway, NJ, 08854, USA.
Small. 2021 Jun;17(22):e2005165. doi: 10.1002/smll.202005165. Epub 2020 Nov 3.
Metal-organic frameworks (MOFs) built on calcium metal (Ca-MOFs) represent a unique subclass of MOFs featuring high stability, low toxicity, and relatively low density. Ca-MOFs show considerable potential for molecular separations, electronic, magnetic, and biomedical applications, although they are not investigated as extensively as transition metal-based MOFs. Compared to MOFs made of other groups of metals, Ca-MOFs may be particularly advantageous for certain applications such as adsorption and storage of light molecules because of their gravimetric benefit, and drug delivery due to their high biocompatibility. This review intends to provide an overview on the recent development of Ca-MOFs, including their synthesis, crystal structures, important properties, and related applications. Various synthetic methods and techniques, types of building blocks, structure and porosity features, selected physical properties, and potential uses will be discussed and summarized. Representative examples will be illustrated for each type of important applications with a focus on their structure-property relations.
基于金属钙的金属有机骨架（Ca-MOFs）代表了一类独特的 MOFs，具有高稳定性、低毒性和相对低密度。Ca-MOFs 在分子分离、电子、磁性和生物医学应用方面具有相当大的潜力，尽管它们的研究不如基于过渡金属的 MOFs 广泛。与由其他金属组制成的 MOFs 相比，Ca-MOFs 由于其重量效益，在某些应用中可能特别有利，例如轻分子的吸附和储存，并且由于其高生物相容性，在药物输送方面也可能有利。
本综述旨在概述 Ca-MOFs 的最新发展，包括它们的合成、晶体结构、重要性质和相关应用。将讨论和总结各种合成方法和技术、构建块类型、结构和孔隙率特征、选定的物理性质以及潜在用途。将针对每种重要应用类型的代表性示例进行说明，并重点介绍它们的结构-性质关系。
