School of Engineering, Newcastle University, Newcastle Upon Tyne NE1 7RU, United Kingdom.
School of Pharmacy, Newcastle University, Newcastle Upon Tyne NE1 7RU, United Kingdom.
Langmuir. 2020 Nov 17;36(45):13396-13407. doi: 10.1021/acs.langmuir.0c00411. Epub 2020 Nov 3.
The concept of slippery lubricant-infused surfaces has shown promising potential in antifouling for controlling detrimental biofilm growth. In this study, nontoxic silicone oil was either impregnated into porous surface nanostructures, referred to as liquid-infused surfaces (LIS), or diffused into a polydimethylsiloxane (PDMS) matrix, referred to as a swollen PDMS (S-PDMS), making two kinds of slippery surfaces. The slippery lubricant layers have extremely low contact angle hysteresis, and both slippery surfaces showed superior antiwetting performances with droplets bouncing off or rolling transiently after impacting the surfaces. We further demonstrated that water droplets can remove dust from the slippery surfaces, thus showing a "cleaning effect". Moreover, "coffee-ring" effects were inhibited on these slippery surfaces after droplet evaporation, and deposits could be easily removed. The clinically biofilm-forming species (as a model system) was used to further evaluate the antifouling potential of the slippery surfaces. The dried biofilm stains could still be easily removed from the slippery surfaces. Additionally, both slippery surfaces prevented around 90% of bacterial biofilm growth after 6 days compared to the unmodified control PDMS surfaces. This investigation also extended across another clinical pathogen, , and showed similar results. The antiwetting and antifouling analysis in this study will facilitate the development of more efficient slippery platforms for controlling biofouling.
滑润剂浸润表面的概念在控制有害生物膜生长的防污方面显示出了有前景的潜力。在这项研究中，无毒硅油要么被注入多孔表面纳米结构中，称为液体浸润表面（LIS），要么扩散到聚二甲基硅氧烷（PDMS）基质中，称为溶胀 PDMS（S-PDMS），形成两种滑润表面。滑润剂层具有极低的接触角滞后，两种滑润表面都表现出优异的抗湿性能，液滴冲击表面后会弹开或短暂滚动。我们进一步证明，水滴可以从滑润表面去除灰尘，从而表现出“清洁效果”。此外，在液滴蒸发后，这些滑润表面上抑制了“咖啡环”效应，并且沉积物可以很容易地去除。临床上形成生物膜的物种（作为模型系统）被进一步用于评估滑润表面的防污潜力。干燥的生物膜污渍仍然可以很容易地从滑润表面去除。此外，与未改性的对照 PDMS 表面相比，两种滑润表面在 6 天后阻止了约 90%的细菌生物膜生长。这项研究还扩展到另一种临床病原体 ，并显示出相似的结果。本研究中的抗湿和防污分析将有助于开发更有效的控制生物污损的滑润平台。
