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黄原胶的化学改性通过接枝共聚:定制的性能和在药物传递和废水处理中的潜在应用。

Chemical modification of xanthan gum through graft copolymerization: Tailored properties and potential applications in drug delivery and wastewater treatment.

机构信息

Department of Chemistry, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, 484887, India.

Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, 484887, India.

出版信息

Carbohydr Polym. 2021 Jan 1;251:117095. doi: 10.1016/j.carbpol.2020.117095. Epub 2020 Sep 16.

Abstract

Xanthan gum (XG) possesses numerous hydroxyl groups, which are the focal points for graft copolymerization of synthetic monomers. A detailed mechanism of graft copolymerization is of utmost importance in obtaining new materials with desirable attributes. The physicochemical, thermal, and morphological changes gained after graft copolymerization is also described. The graft copolymerization can further improve adsorption efficiency of toxic heavy metals and synthetic dyes from wastewater or industrial effluents. The swelling and pH-sensitivity of graft copolymer are attractive features for the purpose of controlled drug delivery. Despite a plethora of reports, comprehensive reviews on XG-based graft copolymers and their potential applications are scarce. Hence, this review undertakes detailed discussion on the synthesis of XG-based graft copolymer, their properties and potential application in drug delivery and wastewater treatment, which would be interesting for the readers and budding scientists to progress further with polysaccharide research and explore new materials for the intended purposes.

摘要

黄原胶(XG)具有许多羟基,这些羟基是合成单体接枝共聚的焦点。接枝共聚的详细机制对于获得具有理想特性的新材料至关重要。接枝共聚后获得的物理化学、热和形态变化也有描述。接枝共聚可以进一步提高有毒重金属和合成染料从废水或工业废水中的吸附效率。接枝共聚物的溶胀和 pH 敏感性是控制药物释放的有吸引力的特性。尽管有大量的报道,但关于基于 XG 的接枝共聚物及其潜在应用的综合评论很少。因此,本综述详细讨论了基于 XG 的接枝共聚物的合成、它们的性质以及在药物输送和废水处理中的潜在应用,这将引起读者和有抱负的科学家的兴趣,进一步推进多糖研究并探索新材料以达到预期目的。

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