Department of Nursing, College of Applied Medical Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Department of Biomedical Sciences, College of Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Nutrients. 2020 Oct 30;12(11):3346. doi: 10.3390/nu12113346.
The study purpose was to investigate the effect of (PV) on urinary biochemical parameters among patients with kidney stones. We conducted a randomized controlled study among 60 patients with kidney stones (size < 10 mm) in the nephrology unit of both government and private hospitals, Al-Ahsa. Urinary volume, calcium, magnesium, potassium, oxalate, uric acid, and power of hydrogen (pH) were assessed before and after the intervention of giving 250 g of PV consumption as an extract thrice weekly (2.2 L to 2.5 L per week) for 6 weeks, which was compared with control. A 't' test was used with the significance at 5%. Mean score of age was 44.5 ± 10.16 in PV group and 43.73 ± 9.79 in control. Four (13.3%) and two (6.7%) had family history of kidney stones. Body mass Index (BMI) mean was 26.44 ± 2.7 and 26.36 ± 2.65 in pre and post-test, respectively, which were significant ( = 0.01017). There were significant changes ( = 0.000) in urine volume from 1962 ± 152.8 to 2005 ± 148.8, calcium 205.4 ± 11.99 to 198.4 ± 12.52, potassium 44.07 ± 3.66 to 52.15 ± 4.37, oxalate 37.12 ± 5.38 to 33.02 ± 5.71, and uric acid 6.88 ± 0.7 to 6.31 ± 0.58. In conclusion, PV is effective management for the patients with kidney stones as it increases the urinary volume and enhances the elimination of small kidney stones.
本研究旨在探讨 PV 对肾结石患者尿生化参数的影响。我们在 Al-Ahsa 的政府和私立医院肾病科进行了一项随机对照研究，纳入了 60 名肾结石（大小<10mm）患者。在干预前和干预后（每周三次给予 250g 的 PV 提取物，每周 2.2 到 2.5 升，持续 6 周）评估了尿容量、钙、镁、钾、草酸盐、尿酸和氢离子浓度（pH），并与对照组进行比较。采用 t 检验，显著性水平为 5%。PV 组的平均年龄为 44.5 ± 10.16 岁，对照组为 43.73 ± 9.79 岁。四例（13.3%）和两例（6.7%）有肾结石家族史。体重指数（BMI）均值分别为 26.44 ± 2.7 和 26.36 ± 2.65，干预前后差异有统计学意义（=0.01017）。尿容量从 1962 ± 152.8 到 2005 ± 148.8、钙从 205.4 ± 11.99 到 198.4 ± 12.52、钾从 44.07 ± 3.66 到 52.15 ± 4.37、草酸盐从 37.12 ± 5.38 到 33.02 ± 5.71、尿酸从 6.88 ± 0.7 到 6.31 ± 0.58 均有显著变化（=0.000）。结论：PV 是肾结石患者的有效治疗方法，可增加尿容量，促进小肾结石的排出。
Zotero 插件