Wang Shenli, Chen Lishui, Yang Haiying, Gu Jinghan, Wang Jing, Ren Fazheng
Beijing Advanced Innovation Center for Food Nutrition and Human Health College of Food Science and Nutrition Engineering China Agricultural University Beijing China.
Brand Food R&D Center Nutrition & Health Research Institute (COFCO-NHRI) Beijing China.
Food Sci Nutr. 2020 Feb 5;8(3):1315-1324. doi: 10.1002/fsn3.1299. eCollection 2020 Mar.
L. is rich in alpha-amylase inhibitor and has been used for reducing glycemia and calories absorption through preventing or delaying the digestion of complex carbohydrate. A randomized, double-blinded, placebo-controlled study was conducted on obese volunteers to evaluate the degree of significate weight loss by regular intake cultivated from Southwestern region of China.
The volunteers were divided into two groups, homogeneous for age, gender, and body weight. extract or placebo was given 2,400 mg per day before each daily meal for 35 consecutive days. Each subject's body weight, fat mass, body mass index, blood biochemical parameters, skinfold fat thickness, and waist/hip circumferences were monitored and analyzed.
As a result, the average amount of weight lost by the extract group was 2.24 kg (average of 0.448 kg per week), compared with a 0.29 kg weight loss (average of 0.058 kg per week) in placebo group after 35 days. The differences between groups were significant ( < .01). The body mass index decreased by an average of 0.79, and the body fat decreased by 1.53% on average compared to baseline ( < .05). The thickness of subcutaneous fat was significantly reduced at the four measurement points, and the decrease of waist circumference and hip circumference was significant as well. No adverse or side effects were observed during the trial period. The results indicate that extract can significantly induce weight loss in a short time period.
L.富含α-淀粉酶抑制剂，已被用于通过预防或延缓复合碳水化合物的消化来降低血糖和热量吸收。对肥胖志愿者进行了一项随机、双盲、安慰剂对照研究，以评估定期摄入源自中国西南地区种植的[提取物名称]后的显著体重减轻程度。
将志愿者按年龄、性别和体重进行分组，每组情况相同。连续35天，在每日每餐之前给每组服用2400毫克提取物或安慰剂。监测并分析每个受试者的体重、脂肪量、体重指数、血液生化参数、皮褶脂肪厚度以及腰臀围。
结果，35天后，提取物组平均体重减轻2.24千克（平均每周0.448千克），而安慰剂组体重减轻0.29千克（平均每周0.058千克）。两组之间的差异具有显著性（P<0.01）。与基线相比，体重指数平均下降0.79，体脂平均下降1.53%（P<0.05）。在四个测量点皮下脂肪厚度均显著降低，腰围和臀围的减小也很显著。在试验期间未观察到不良或副作用。结果表明，[提取物名称]提取物可在短时间内显著诱导体重减轻。
