Reed Nick, Balega Janos, Barwick Tara, Buckley Lynn, Burton Kevin, Eminowicz Gemma, Forrest Jenny, Ganesan Raji, Harrand Rosie, Holland Cathrine, Howe Tamara, Ind Thomas, Iyer Rema, Kaushik Sonali, Music Robert, Sadozye Azmat, Shanbhag Smruta, Siddiqui Nadeem, Syed Sheeba, Percival Natalie, Whitham Natasha Lauren, Nordin Andy, Fotopoulou Christina
Beatson Oncology Centre, Glasgow, United Kingdom.
City Hospital Birmingham, United Kingdom.
Eur J Obstet Gynecol Reprod Biol. 2021 Jan;256:433-465. doi: 10.1016/j.ejogrb.2020.08.020. Epub 2020 Sep 29.
Cervix cancer in many countries is declining and screening programmes and immunisation will reduce the incidence in the next few decades. This guideline attempts to cover management of invasive disease reflecting diagnosis and imaging including new imaging and sentinel lymph node biopsies. Smaller volume disease is usually managed surgically whereas advanced disease is treated with (chemo)- radiation. It also includes discussion of fertility sparing procedures. Practices are changing frequently for all aspects of care usually in attempts to reduce complications and improve quality of life. The management of advanced disease is treated by chemotherapy and the use of newer agents is also discussed. Other sections discuss specialist situations such as cancer in pregnancy, rare cervical tumours, late effects and supportive measures and fertility preserving approaches.
在许多国家,宫颈癌发病率正在下降,筛查计划和免疫接种将在未来几十年降低其发病率。本指南试图涵盖浸润性疾病的管理,反映诊断和成像,包括新的成像技术和前哨淋巴结活检。较小体积的疾病通常通过手术治疗,而晚期疾病则采用(化疗)放疗。它还包括对保留生育功能手术的讨论。护理的各个方面的做法都在频繁变化,通常是为了减少并发症和提高生活质量。晚期疾病的治疗采用化疗,也讨论了新型药物的使用。其他章节讨论了特殊情况,如妊娠合并癌症、罕见的宫颈肿瘤、远期效应和支持措施以及保留生育功能的方法。