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新鲜骨软骨同种异体移植(FOCAT)治疗 198 平方毫米距骨骨软骨病变(OLT)的确定性治疗:病例报告。

Fresh osteochondral allograft transplantation (FOCAT) for definitive management of a 198 square millimeter osteochondral lesion of the talus (OLT): A case report.

机构信息

Westside regional, 8201 Broward Blvd, 33324, Plantation, USA.

Westside regional, 8201 Broward Blvd, 33324, Plantation, USA.

出版信息

Foot (Edinb). 2021 Mar;46:101639. doi: 10.1016/j.foot.2019.09.001. Epub 2019 Nov 11.

Abstract

An osteochondral lesion of the talus (OLT) is an idiopathic acquired lesion of the subchondral bone that can lead to debilitating sequelae. The causes of OLT's are still debatable, however, most agree that the etiology is repetitive microtrauma associated with vascular impairment. OLTs are most commonly described in the medial portion of the talus, while lateral involvement is less frequent. If not properly recognized and treated, an OLT may lead to numerous secondary conditions including premature osteoarthritis and functional limitations of the ankle joint. Multiple surgical and non-surgical treatment modalities have been described with varying results. Treatments are usually guided by the patients age, onset of symptoms, severity, and the disease stage according to the Berndt and Harty classification. Recent literature recommends curettage, drilling, or microfracture techniques for lesions which are no larger than 15mm in diameter and no deeper than 7mm. On the other hand, for large lesions or lesions that failed from primary bone marrow stimulation, surgery should be considered for autologous chondrocyte implantation (ACI), osteochondral autograft transplantation (OATs or mosaicplasty), or osteochondral allograft transplantation [1]. This case study examines surgical treatment of an extensive OLT in a 53 year old man who suffered with continuous ankle pain for over 10 years, misdiagnosed as ankle joint arthritis. Level of clinical evidence: Level of evidence 4.

摘要

距骨骨软骨损伤(OLT)是一种特发性获得性软骨下骨病变,可导致致残性后遗症。OLT 的病因仍存在争议,但大多数人认为其病因是与血管损伤相关的反复微创伤。OLT 最常发生在距骨的内侧部分,而外侧受累则较少见。如果未得到正确识别和治疗,OLT 可能会导致多种继发性疾病,包括早期骨关节炎和踝关节功能受限。已经描述了多种手术和非手术治疗方法,其结果各不相同。根据 Berndt 和 Harty 分类,治疗方法通常根据患者的年龄、症状出现时间、严重程度和疾病阶段来指导。最近的文献建议对直径不超过 15mm 且深度不超过 7mm 的病变采用刮除、钻孔或微骨折技术。另一方面,对于大的病变或初次骨髓刺激失败的病变,应考虑进行自体软骨细胞移植(ACI)、骨软骨自体移植(OAT 或马赛克plasty)或骨软骨同种异体移植[1]。本病例研究检查了一名 53 岁男性的广泛 OLT 的手术治疗,该患者持续踝关节疼痛超过 10 年,误诊为踝关节关节炎。临床证据水平:证据水平 4。

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