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富含γ-氨基丁酸的茶作为神经营养保健品。

GABA-enriched teas as neuro-nutraceuticals.

作者信息

Hinton Tina, Johnston Graham A R

机构信息

Pharmacology, School of Medical Sciences, Faculty of Medicine and Health Sciences, The University of Sydney, Sydney, 2006, Australia.

Pharmacology, School of Medical Sciences, Faculty of Medicine and Health Sciences, The University of Sydney, Sydney, 2006, Australia.

出版信息

Neurochem Int. 2020 Dec;141:104895. doi: 10.1016/j.neuint.2020.104895. Epub 2020 Nov 2.

Abstract

Teas enriched in GABA are consumed for their beneficial effects on blood pressure, stress and anxiety. These effects may involve actions of GABA on the central and peripheral nervous systems. The anaerobic procedures for the production of GABA-enriched teas increase GABA levels by 10-20 times. They also significantly alter the levels of other constituents that may interact with the actions of GABA. These include epigallocatechin gallate, caffeine and theanine. The possible interactions of these active constituents make the understanding of the effects of GABA-enriched teas complex. More data is needed to establish where and how GABA is acting following consumption of GABA-enriched teas. While there is considerable evidence that such GABA is acting on GABA receptors in the periphery, there is rather less evidence that is acting directly in the brain. Certainly, there is more to the action of GABA-enriched teas than GABA itself.

摘要

富含γ-氨基丁酸(GABA)的茶因其对血压、压力和焦虑的有益影响而被饮用。这些影响可能涉及GABA对中枢和外周神经系统的作用。生产富含GABA的茶的厌氧程序可使GABA水平提高10至20倍。它们还会显著改变其他可能与GABA作用相互影响的成分的水平。这些成分包括表没食子儿茶素没食子酸酯、咖啡因和茶氨酸。这些活性成分之间可能的相互作用使得理解富含GABA的茶的效果变得复杂。需要更多数据来确定饮用富含GABA的茶后GABA的作用部位和作用方式。虽然有大量证据表明这种GABA在外周作用于GABA受体,但较少有证据表明它直接在大脑中起作用。当然,富含GABA的茶的作用不仅仅取决于GABA本身。

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