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草药茶在调节细胞内稳态和自噬中的作用及其对整体健康调节的意义。

Role of Herbal Teas in Regulating Cellular Homeostasis and Autophagy and Their Implications in Regulating Overall Health.

机构信息

Natural Products for Neuroprotection and Anti-Ageing Research Unit, Chulalongkorn University, Bangkok 10330, Thailand.

Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

出版信息

Nutrients. 2021 Jun 23;13(7):2162. doi: 10.3390/nu13072162.

Abstract

Tea is one of the most popular and widely consumed beverages worldwide, and possesses numerous potential health benefits. Herbal teas are well-known to contain an abundance of polyphenol antioxidants and other ingredients, thereby implicating protection and treatment against various ailments, and maintaining overall health in humans, although their mechanisms of action have not yet been fully identified. Autophagy is a conserved mechanism present in organisms that maintains basal cellular homeostasis and is essential in mediating the pathogenesis of several diseases, including cancer, type II diabetes, obesity, and Alzheimer's disease. The increasing prevalence of these diseases, which could be attributed to the imbalance in the level of autophagy, presents a considerable challenge in the healthcare industry. Natural medicine stands as an effective, safe, and economical alternative in balancing autophagy and maintaining homeostasis. Tea is a part of the diet for many people, and it could mediate autophagy as well. Here, we aim to provide an updated overview of popular herbal teas' health-promoting and disease healing properties and in-depth information on their relation to autophagy and its related signaling molecules. The present review sheds more light on the significance of herbal teas in regulating autophagy, thereby improving overall health.

摘要

茶是全球最受欢迎和广泛消费的饮料之一,具有许多潜在的健康益处。众所周知,草本茶含有丰富的多酚类抗氧化剂和其他成分,因此可以预防和治疗各种疾病,并保持人类的整体健康,尽管其作用机制尚未完全确定。自噬是一种存在于生物体内的保守机制,它维持着基础细胞的内稳态,对于介导多种疾病的发病机制至关重要,包括癌症、II 型糖尿病、肥胖症和阿尔茨海默病。这些疾病的患病率不断上升,可能归因于自噬水平的失衡,这给医疗保健行业带来了相当大的挑战。天然药物是平衡自噬和维持内稳态的有效、安全和经济的替代品。茶是许多人的饮食的一部分,它也可以介导自噬。在这里,我们旨在提供对流行草本茶的促进健康和治疗疾病特性的最新概述,并深入了解它们与自噬及其相关信号分子的关系。本综述更深入地探讨了草本茶在调节自噬、从而改善整体健康方面的重要性。

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