Departament of Veterinary Clinic and Surgery, School of Agrarian and Veterinary Sciences, São Paulo State University (UNESP/FCAV), Jaboticabal, SP, Brazil.
Departament of Veterinary Clinic and Surgery, School of Agrarian and Veterinary Sciences, São Paulo State University (UNESP/FCAV), Jaboticabal, SP, Brazil.
Top Companion Anim Med. 2021 Mar;42:100489. doi: 10.1016/j.tcam.2020.100489. Epub 2020 Nov 1.
The aim of this study was to evaluate the prevalence and antimicrobial resistance profile of bacterial species isolated from infected sites of canines. All samples were collected from canine patients who received clinical or surgical care at the veterinary teaching hospital between March 2016 and November 2017. The samples were analyzed in a private pathology laboratory. A descriptive analysis of 295 antimicrobial susceptibility test reports was performed. Staphylococcus spp. (104/295 [35.25%]), Escherichia coli (100/295 [33.90%]), Proteus spp. (44/295 [14.92%]), Pseudomonas spp. (25/295 [8.47%]), and Klebsiella spp. (20/295 [6.78%]) were more frequently isolated, and a high incidence of multidrug resistance was observed (69,83% [206/295]). Methicillin-resistant Staphylococcus spp. accounted for 33% (33/100) of the Staphylococcus strains. Enterobacteriaceae cefotaxime resistance constituted 22.82 ± 4.49% and Enterobacteriaceae imipenem resistance constituted 5% (1/20) for Klebsiella spp., 5% (5/100) for E coli, and 6.82% (3/44) for Proteus spp. Pseudomonas spp. strains accounted for 8% (2/25) of imipenem resistance and 45.45% (10/22) of polymyxin B resistance. Our findings revealed a high rate of multidrug-resistant bacteria involvement in the infectious process of dogs. From the perspective of the One Health scenario, our results showed alarming data, given the high risk of resistant-strain dissemination between animals, owners, and healthcare professionals. There is an urgent need for strategies to control and prevent the evolution of new multidrug-resistant bacteria in veterinary hospitals. It is also crucial to understand and emphasize the role of veterinary professionals in this public health battle.
本研究旨在评估从犬感染部位分离的细菌种类的流行率和抗菌药物耐药谱。所有样本均采集自 2016 年 3 月至 2017 年 11 月期间在兽医教学医院接受临床或手术治疗的犬患者。样本在一家私立病理实验室进行分析。对 295 份抗菌药物敏感性试验报告进行了描述性分析。葡萄球菌属（104/295 [35.25%]）、大肠杆菌（100/295 [33.90%]）、变形杆菌属（44/295 [14.92%]）、铜绿假单胞菌属（25/295 [8.47%]）和克雷伯菌属（20/295 [6.78%]）的分离率较高，且观察到多药耐药的发生率较高（69.83% [206/295]）。耐甲氧西林葡萄球菌属占葡萄球菌株的 33%（33/100）。肠杆菌科头孢噻肟耐药率为 22.82±4.49%，肠杆菌科亚胺培南耐药率为 5%（1/20），克雷伯菌属为 5%（5/100），大肠杆菌为 6.82%（3/44），变形杆菌属为 6.82%（3/44）。铜绿假单胞菌属菌株对亚胺培南的耐药率为 8%（2/25），对多黏菌素 B 的耐药率为 45.45%（10/22）。我们的研究结果表明，在犬感染过程中，涉及多种耐药细菌的比率较高。从“同一健康”的角度来看，鉴于动物、主人和医护人员之间耐药菌株传播的高风险，我们的研究结果显示了令人担忧的数据。因此，迫切需要制定控制和预防兽医医院新的多药耐药细菌出现的策略。了解和强调兽医专业人员在这场公共卫生斗争中的作用也至关重要。
