2008 年至 2018 年间，从加拿大一家兽医教学医院收治的马匹中分离出的耐甲氧西林 spp.的回顾性研究。
A retrospective study on methicillin-resistant spp. isolated from horses admitted to a Canadian veterinary teaching hospital between 2008 and 2018.
机构信息
Département de sciences cliniques, Faculté de médecine vétérinaire, Université de Montréal, 3200, rue Sicotte, Saint-Hyacinthe, Québec J2S 2M2 (Roudaud, Allano, Sauvé); Bacteriology Diagnostic Laboratory, Complexe de Diagnostic et d'Épidémiosurveillance Vétérinaires du Québec, Ministère de l'Agriculture, des Pêcheries et de l'Alimentation du Québec and Faculté de médecine vétérinaire, Université de Montréal, 3220, rue Sicotte, Saint-Hyacinthe, Québec J2S 2M2 (Fairbrother).
出版信息
Can Vet J. 2020 Nov;61(11):1197-1202.
The goals of this retrospective study were to: determine the frequency of methicillin-resistant spp. (MRS) isolated from horses admitted to an equine veterinary teaching hospital in Quebec from 2008 to 2018, investigate the patterns of antimicrobial resistance (AMR), and evaluate the distribution of MRS and methicillin-sensitive spp. (MSS) by body site. During this period, 311 spp. were isolated from 273 horses and 127 of these isolates were submitted to antimicrobial susceptibility testing. Of these 127 isolates, 24 (18.9%) were MRS, and among the ( = 76), 19 (25%) were MRS. The odds of detecting an MRS increased (25%) each year [95% confidence interval (CI) (1% to 55%), = 0.039]. The highest frequencies of resistance were to tetracycline and gentamicin. Among the MRS isolates, 12% were susceptible to both tetracycline and gentamicin. The most frequently sampled body sites were "soft-tissues." There was no significant difference ( = 0.93) in the body site distribution of MRS and MSS isolates.
本回顾性研究的目的为
确定 2008 年至 2018 年期间从魁北克省一所兽医教学医院收治的马匹中分离出的耐甲氧西林 （MRS）的频率，调查抗生素耐药性（AMR）模式，并评估 MRS 和甲氧西林敏感 （MSS）在不同部位的分布。在此期间，从 273 匹马中分离出 311 株 ，其中 127 株被送进行抗生素药敏试验。在这 127 株分离株中，24 株（18.9%）为 MRS，在 76 株 中，19 株（25%）为 MRS。每年检测到 MRS 的几率增加（25%）[95%置信区间（CI）（1%至 55%）， = 0.039]。耐药率最高的是四环素和庆大霉素。在 MRS 分离株中，12%对四环素和庆大霉素均敏感。采样最频繁的部位是“软组织”。MRS 和 MSS 分离株在不同部位的分布无显著差异（ = 0.93）。
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