Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan
In Vivo. 2020 Nov-Dec;34(6):3589-3595. doi: 10.21873/invivo.12203.
Little is known about the clinical outcomes of acute myocardial infarction (AMI) in patients with a history of malignant tumor (MT).
We retrospectively studied 1,295 consecutive patients with AMI who underwent primary percutaneous coronary intervention within 24 hours of onset. The patients were divided into two groups: those with a history of MT (MT group, n=50) and those without (non-MT group, n=1,245).
The MT group was older, and had lower hemoglobin, total protein, and albumin levels. All-cause mortality and re-admission rates due to acute decompensated heart failure (ADHF) were significantly higher in the MT group. Multivariate analysis showed that a history of MT was an independent predictor for all-cause mortality and re-admission due to ADHF.
The clinical outcomes of patients with AMI with a history of MT are poor, and a history of MT is an independent predictor for all-cause mortality and re-admission due to ADHF. These patients may need careful risk management for heart failure to avoid re-admissions due to ADHF.
对于有恶性肿瘤（MT）病史的急性心肌梗死（AMI）患者，其临床结局知之甚少。
我们回顾性研究了 1295 例在发病后 24 小时内接受直接经皮冠状动脉介入治疗的 AMI 连续患者。患者分为两组：有 MT 病史（MT 组，n=50）和无 MT 病史（非 MT 组，n=1245）。
MT 组年龄较大，血红蛋白、总蛋白和白蛋白水平较低。MT 组全因死亡率和因急性失代偿性心力衰竭（ADHF）再入院率均显著较高。多变量分析显示，MT 病史是全因死亡率和因 ADHF 再入院的独立预测因素。
有 MT 病史的 AMI 患者的临床结局较差，MT 病史是全因死亡率和因 ADHF 再入院的独立预测因素。这些患者可能需要进行心力衰竭的仔细风险管理，以避免因 ADHF 再入院。
