心肌梗死后应激性心肌病与急性冠状动脉综合征患者的死亡率与左心室射血分数的相关性。
Association Between Mortality and Left Ventricular Ejection Fraction in Patients With Takotsubo Syndrome Acute Coronary Syndrome.
机构信息
First Department of Medicine, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany.
DZHK (German Center for Cardiovascular Research), Partner Site, Heidelberg-Mannheim, Mannheim, Germany.
出版信息
In Vivo. 2020 Nov-Dec;34(6):3639-3648. doi: 10.21873/invivo.12210.
BACKGROUND/AIM: The association between ejection fraction (EF) and mortality in TTS patients as compared to ACS is limited. This study aims to investigate the association between EF and clinical outcomes in patients with TTS as compared to ACS.
PATIENTS AND METHODS
This study compared in-hospital, and long-term incidence of clinical outcomes for 5 years in patients with TTS and ACS. The study was composed of two groups EF≥35% and EF<35%.
RESULTS
The long-term mortality of the EF≥35% for 5 years was significantly higher in TTS patients as compared to ACS (18.1% vs. 7.7%, log-Rank; p<0.01). Irrespective of EF, a non-cardiovascular death was significantly higher in TTS as compared to ACS patients with EF≥35 (6.4% vs. 2.1%; p=0.02) and with EF<35% (21.4% vs. 7.5%; p=0.03).
CONCLUSION
The long-term mortality is significantly higher in TTS as compared to ACS dominated by a non-cardiovascular cause of death at 5-years-follow-up.
背景/目的：射血分数（EF）与 TTS 患者死亡率之间的关联与 ACS 相比受到限制。本研究旨在调查 TTS 患者 EF 与临床结局之间的关系与 ACS 相比。
患者和方法
本研究比较了 TTS 和 ACS 患者住院期间和 5 年内的临床结局发生率。该研究由 EF≥35%和 EF<35%两组组成。
结果
EF≥35%的 TTS 患者 5 年的长期死亡率明显高于 ACS（18.1% vs. 7.7%，对数秩检验；p<0.01）。无论 EF 如何，EF≥35 的 TTS 患者的非心血管死亡明显高于 ACS（6.4% vs. 2.1%；p=0.02）和 EF<35%（21.4% vs. 7.5%；p=0.03）。
结论
在 5 年随访中，TTS 的长期死亡率明显高于 ACS，主要是非心血管死亡原因。
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