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中风减压开颅术后无症状性脑脓肿——两例报告及文献复习

Asymptomatic Brain Abscess Following Decompressive Craniotomy for Stroke - A Report of Two Cases and Review of the Literature.

作者信息

Kutty Raja K, Sreemathyamma Sunilkumar Balakrishnan, Sivanandapanicker Jyothish Laila, Vijayan Abhishek, Asher Prasanth, Peethambaran Anilkumar

机构信息

Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India.

出版信息

Asian J Neurosurg. 2020 Aug 28;15(3):781-785. doi: 10.4103/ajns.AJNS_51_20. eCollection 2020 Jul-Sep.

DOI:10.4103/ajns.AJNS_51_20
PMID:33145255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7591207/
Abstract

Stroke is a significant health problem in both developed and developing nations. The treatment strategies of stroke differ among various centers depending on the available expertise. Nevertheless, stroke contributes to a major economic burden for patients and health institutions. The recovery period after stroke is a critical period wherein various complications can develop in survivors. Among these multiple complications, the formation of brain abscess in the infarcted brain tissue is rare and less well described in the literature. Fever or signs of raised intracranial pressure are the usual manifestation of poststroke brain abscess. We present two unique cases of large brain abscess in patients who survived a malignant stroke. Both the patients were recuperating well after decompressive craniectomy for stroke without any signs of intracranial infection or raised intracranial pressure. Both the patients underwent open drainage of brain abscess, followed by delayed cranioplasty. There are only a few cases of brain abscess reported in the literature in patients who underwent decompressive craniectomy for stroke.

摘要

中风在发达国家和发展中国家都是一个重大的健康问题。中风的治疗策略因各中心现有的专业知识不同而有所差异。尽管如此,中风给患者和医疗机构带来了重大的经济负担。中风后的恢复期是一个关键时期,在此期间幸存者可能会出现各种并发症。在这些多种并发症中,梗死脑组织中形成脑脓肿的情况较为罕见,且文献中对此描述较少。发热或颅内压升高的迹象是中风后脑脓肿的常见表现。我们报告了两例恶性中风幸存者发生大脑脓肿的独特病例。两名患者在接受中风减压颅骨切除术后恢复良好,没有任何颅内感染或颅内压升高的迹象。两名患者均接受了脑脓肿开放引流,随后进行了延迟颅骨成形术。文献中报道的因中风接受减压颅骨切除术的患者发生脑脓肿的病例很少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/cdd1af348d3a/AJNS-15-781-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/4697e71261cd/AJNS-15-781-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/db85a5351707/AJNS-15-781-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/7d938b2253e0/AJNS-15-781-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/e469154d6def/AJNS-15-781-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/04832b8f0d29/AJNS-15-781-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/cdd1af348d3a/AJNS-15-781-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/4697e71261cd/AJNS-15-781-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/db85a5351707/AJNS-15-781-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/7d938b2253e0/AJNS-15-781-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/e469154d6def/AJNS-15-781-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/04832b8f0d29/AJNS-15-781-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7581/7591207/cdd1af348d3a/AJNS-15-781-g006.jpg

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本文引用的文献

1
Incidence & prevalence of stroke in India: A systematic review.印度中风的发病率和患病率:一项系统综述。
Indian J Med Res. 2017 Aug;146(2):175-185. doi: 10.4103/ijmr.IJMR_516_15.
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Secondary cerebral abscess of an ischemic stroke treated by thrombectomy.经血栓切除术治疗的缺血性卒中继发性脑脓肿
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CONSORT: May stereotactic intracavity administration of antibiotics shorten the course of systemic antibiotic therapy for brain abscesses?
CONSORT:立体定向腔内给予抗生素能否缩短脑脓肿全身抗生素治疗的疗程?
Medicine (Baltimore). 2017 May;96(21):e6359. doi: 10.1097/MD.0000000000006359.
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Brain Infarct and Abscess-A Very Common Disease and a Rare Association.脑梗死与脑脓肿——一种常见疾病与罕见关联
World Neurosurg. 2016 Sep;93:476. doi: 10.1016/j.wneu.2016.05.098.
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Ischemia, Immunosuppression and Infection--Tackling the Predicaments of Post-Stroke Complications.缺血、免疫抑制与感染——应对中风后并发症的困境
Int J Mol Sci. 2016 Jan 5;17(1):64. doi: 10.3390/ijms17010064.
6
An Intracranial Petri Dish? Formation of Abscess in Prior Large Stroke After Decompressive Hemicraniectomy.颅内培养皿?减压性颅骨切除术后既往大面积脑梗死区域脓肿的形成
World Neurosurg. 2015 Nov;84(5):1495.e5-9. doi: 10.1016/j.wneu.2015.05.013. Epub 2015 May 16.
7
Role of decompressive hemicraniectomy in extensive middle cerebral artery strokes: a meta-analysis of randomised trials.减压性颅骨切除术在大面积大脑中动脉卒中中的作用:一项随机试验的荟萃分析。
Intern Med J. 2015 Jul;45(7):711-7. doi: 10.1111/imj.12724.
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[Cerebral abscess over a previous ischemic infarction].[既往缺血性梗死灶上的脑脓肿]
Enferm Infecc Microbiol Clin. 2014 Jan;32(1):60-1. doi: 10.1016/j.eimc.2013.05.007. Epub 2013 Jul 30.
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BMC Neurol. 2012 Nov 5;12:133. doi: 10.1186/1471-2377-12-133.
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