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光学相干断层扫描血管造影在妊娠相关性中心性浆液性脉络膜视网膜病变中的应用价值

Utility of optical coherence tomography angiography in pregnancy-associated central serous chorioretinopathy.

作者信息

Pole Cameron, Gaw Stephanie Stephanie L, Tsui Irena Irena

机构信息

Retina Division, Stein Eye Institute, University of California Los Angeles, 200 Stein Plaza, Los Angeles, CA, 90095, USA.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 550 16th St, Box 0132, San Francisco, CA, 94143, USA.

出版信息

Am J Ophthalmol Case Rep. 2020 Oct 22;20:100979. doi: 10.1016/j.ajoc.2020.100979. eCollection 2020 Dec.

DOI:10.1016/j.ajoc.2020.100979
PMID:33145456
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7595881/
Abstract

PURPOSE

To describe a case of pregnancy-related central serous chorioretinopathy (pCSCR) and the utility of monitoring with optical coherence tomography (OCT) and OCT angiography (OCTA).

OBSERVATIONS

A 34-year-old female in her third trimester of pregnancy presented with symptomatic visual disturbances of the right eye. Medical history was otherwise unremarkable. Optical coherence tomography (OCT) disclosed a serous retinal detachment with trace subretinal fibrin and elevation of the retinal pigment epithelium (RPE). OCT angiography (OCTA) demonstrated absence of choroidal neovascular membrane (CNV). It was decided to monitor with weekly OCTs until delivery, after which the patient had full resolution of symptoms and subretinal fluid.

CONCLUSIONS AND IMPORTANCE

Pregnancy-related CSCR may be complicated by fibrin deposition and RPE changes suspicious for CNV. This provides evidence of the utility of OCT for monitoring pCSCR progression and of OCTA to non-invasively assess presence of CNV.

摘要

目的

描述一例妊娠相关性中心性浆液性脉络膜视网膜病变(pCSCR)病例以及光学相干断层扫描(OCT)和 OCT 血管造影(OCTA)在监测中的应用。

观察结果

一名妊娠晚期的 34 岁女性出现右眼有症状的视觉障碍。其他病史无异常。光学相干断层扫描(OCT)显示浆液性视网膜脱离伴微量视网膜下纤维蛋白及视网膜色素上皮(RPE)隆起。OCT 血管造影(OCTA)显示无脉络膜新生血管膜(CNV)。决定每周进行 OCT 监测直至分娩,之后患者症状完全缓解且视网膜下液消失。

结论与意义

妊娠相关性 CSCR 可能并发纤维蛋白沉积和疑似 CNV 的 RPE 改变。这为 OCT 监测 pCSCR 进展及 OCTA 无创评估 CNV 的存在提供了有用证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e976/7595881/a2fbac5337a9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e976/7595881/7745c482a482/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e976/7595881/a2fbac5337a9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e976/7595881/7745c482a482/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e976/7595881/a2fbac5337a9/gr2.jpg

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本文引用的文献

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Prog Retin Eye Res. 2019 Nov;73:100770. doi: 10.1016/j.preteyeres.2019.07.003. Epub 2019 Jul 15.
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Management of Retinal Diseases in Pregnant Patients.妊娠患者视网膜疾病的管理
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Risk factors for central serous chorioretinopathy in pregnant Japanese women.日本孕妇中心性浆液性脉络膜视网膜病变的危险因素。
J Obstet Gynaecol Res. 2017 May;43(5):866-872. doi: 10.1111/jog.13289. Epub 2017 Feb 11.
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Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration.年龄相关性黄斑变性中1型新生血管的光学相干断层扫描血管造影
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