Two new compounds with anti-inflammatory activity from .

A new phenolic glycoside, chinenside A (), and a new megastigmane glycoside, chinenionside A (), together with twelve known compounds (), were isolated from the roots of . Their structures were deduced on the basis of extensive spectroscopic analyses and comparison with data reported in the literature. The anti-inflammatory activity in vitro of all 13 phenolic glycosides was evaluated against lipopolysaccharide-induced mouse macrophage RAW264.7 cells. The compounds , , and potentially inhibited the productions of nitric oxide (NO), prostaglandin (PEG), tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β) and interleukin 6 (IL-6). Compound (50 μM) showed stronger anti-inflammatory activity than Triptolide (TPL, 20 nm).