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原发性血栓性血小板减少性紫癜患者血清中的血小板定向抗体。

Platelet-directed antibody in the serum of patients with primary thrombotic thrombocytopenic purpura.

作者信息

Lazarchick J, Graddick S L, Hall S A, Genco P V

机构信息

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425.

出版信息

Ann Clin Lab Sci. 1987 Sep-Oct;17(5):339-44.

PMID:3314658
Abstract

Utilizing two platelet antibody assay systems, flow cytometric analysis and a microcytotoxicity assay, it was possible to demonstrate for the first time platelet-directed antibody in the sera of three of six patients with primary thrombotic thrombocytopenic purpura. These results lend support for an immune-mediated pathologic process in some patients with this disorder.

摘要

利用两种血小板抗体检测系统、流式细胞术分析和微量细胞毒性检测,首次在6例原发性血栓性血小板减少性紫癜患者中的3例血清中证实了血小板定向抗体。这些结果支持了该疾病某些患者存在免疫介导的病理过程。

相似文献

1
Platelet-directed antibody in the serum of patients with primary thrombotic thrombocytopenic purpura.原发性血栓性血小板减少性紫癜患者血清中的血小板定向抗体。
Ann Clin Lab Sci. 1987 Sep-Oct;17(5):339-44.
2
[An autopsy case of thrombotic thrombocytopenic purpura (TTP) complicated with systemic lupus erythematosus (SLE)--demonstration of anti-platelet antibody (author's transl)].
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Detection of platelet antibodies by flow cytometric analysis.通过流式细胞术分析检测血小板抗体。
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4
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Immunologic and other factors in thrombotic thrombocytopenic purpura (TTP).
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Antibody binding to platelet antigens in acute and chronic idiopathic thrombocytopenic purpura: a platelet membrane ELISA for the detection of antiplatelet antibodies in serum.急性和慢性特发性血小板减少性紫癜中抗体与血小板抗原的结合:一种用于检测血清中抗血小板抗体的血小板膜酶联免疫吸附测定法。
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[Determination of platelet-associate autoantibodies against platelet-specific receptors by cytometric bead array and its clinical application in idiopathic thrombocytopenic purpura].[应用流式细胞仪微球阵列技术检测血小板特异性受体相关自身抗体及其在特发性血小板减少性紫癜中的临床应用]
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Platelet antibody in idiopathic thrombocytopenic purpura and other thrombocytopenias. A quantitative, sensitive, and rapid assay.特发性血小板减少性紫癜及其他血小板减少症中的血小板抗体。一种定量、灵敏且快速的检测方法。
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Flow cytometric analysis of anti-platelet antibodies in idiopathic thrombocytopenic purpura.特发性血小板减少性紫癜中抗血小板抗体的流式细胞术分析。
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