原发性血栓性血小板减少性紫癜患者血清中的血小板定向抗体。
Platelet-directed antibody in the serum of patients with primary thrombotic thrombocytopenic purpura.
作者信息
Lazarchick J, Graddick S L, Hall S A, Genco P V
机构信息
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425.
出版信息
Ann Clin Lab Sci. 1987 Sep-Oct;17(5):339-44.
PMID:3314658
Abstract
Utilizing two platelet antibody assay systems, flow cytometric analysis and a microcytotoxicity assay, it was possible to demonstrate for the first time platelet-directed antibody in the sera of three of six patients with primary thrombotic thrombocytopenic purpura. These results lend support for an immune-mediated pathologic process in some patients with this disorder.
摘要
利用两种血小板抗体检测系统、流式细胞术分析和微量细胞毒性检测，首次在6例原发性血栓性血小板减少性紫癜患者中的3例血清中证实了血小板定向抗体。这些结果支持了该疾病某些患者存在免疫介导的病理过程。
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