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腹腔镜Treitz 角肿瘤节段切除术:具有挑战性但可行的手术选择。回顾性病例系列分析结果。

Laparoscopic segmental resection for tumours of the Angle of Treitz: a challenging but feasible surgical option. Results from a retrospective case-series analysis.

机构信息

Department of General and Oncological Minimally Invasive Surgery, University Federico II of Naples, Via Pansini 5 7th Building, Naples, Italy.

Department of General Surgery, Azienda Ospedaliera Dei Colli, Monaldi Hospital, Naples, Italy.

出版信息

Updates Surg. 2021 Feb;73(1):179-186. doi: 10.1007/s13304-020-00910-7. Epub 2020 Nov 4.

Abstract

Tumours of the small intestine are rare and account for about 5% of gastrointestinal tract neoplasms. The angle of Treitz (AT) could be defined as the intestinal loop comprised between the third duodenal portion and the first 10 cm of jejunum. A gold standard surgical treatment for AT neoplasm has not yet been well defined. This paper is focused on a very rare disease and at the best of our knowledge this is the largest case series in the literature about the Laparoscopic Segmental Resection (LSR) of AT tumours. Using a prospectively collected database, all data of consecutive patients, from January 2007 to May 2019, who underwent LSR for AT tumours at two different institutions were analysed. Patients' demographics, intra and post-operative data, 30-day mortality and overall survival were collected. A total of 16 patients were retrieved from our database. The mean operative time was 206,5 ± 79 min. Conversion to open surgery was needed in two cases due to tumor size and, respectively, invasion of the transverse colon which required a multivisceral resection. The mean distal and proximal resection margins were 7.4 ± 2.2 and 3.9 ± 1.2 cm. The median number of harvested nodes was 9 ± 3. Pathological diagnosis was GIST in 11 cases, adenocarcinoma in 4 and sarcoma in 1 case. In conclusion, in experienced hands, LSR appears to be a safe and effective treatment option for tumours of the AT. Prospective studies are needed to confirm these findings.

摘要

小肠肿瘤很少见,占胃肠道肿瘤的 5%左右。Treitz 角(AT)可定义为十二指肠第三段和空肠第一 10cm 之间的肠环。AT 肿瘤的金标准手术治疗尚未得到很好的定义。本文专注于一种非常罕见的疾病,据我们所知,这是文献中关于 AT 肿瘤腹腔镜节段切除术(LSR)的最大系列病例。使用前瞻性收集的数据库,分析了 2007 年 1 月至 2019 年 5 月在两个不同机构接受 LSR 治疗 AT 肿瘤的连续患者的所有数据。收集了患者的人口统计学、围手术期数据、30 天死亡率和总体生存率。从我们的数据库中检索到 16 名患者。平均手术时间为 206.5±79 分钟。由于肿瘤大小和分别需要多脏器切除的横结肠侵犯,有两例需要转为开放性手术。远端和近端切除的平均边缘分别为 7.4±2.2cm 和 3.9±1.2cm。采集的淋巴结中位数为 9±3 个。病理诊断为 GIST 11 例,腺癌 4 例,肉瘤 1 例。总之,在有经验的医生手中,LSR 似乎是 AT 肿瘤的一种安全有效的治疗选择。需要前瞻性研究来证实这些发现。

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