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地黄(Rehmannia glutinosa)生物合成具有高抗菌和催化活性的银纳米粒子。

Biogenic Synthesis of Silver Nanoparticles with High Antimicrobial and Catalytic Activities using Sheng Di Huang (Rehmannia glutinosa).

机构信息

Department of Chemistry, Faculty of Science, National University of Singapore, 3 Science Drive 3, Singapore, 117543, Singapore.

Department of Biological Science and Special Programme in Science, Faculty of Science, National University of Singapore, 6 Science Drive 2, Singapore, 117546, Singapore.

出版信息

Chem Asian J. 2021 Feb 1;16(3):237-246. doi: 10.1002/asia.202001146. Epub 2021 Jan 4.

Abstract

Silver nanoparticles (AgNPs) are widely sought after for a variety of biomedical and environmental applications due to their antimicrobial and catalytic properties. We present here a green and simple synthesis of AgNPs utilizing traditional Chinese medicinal herbs. The screening of 20 aqueous herb extracts shows that Sheng Di Huang (Rehmannia glutinosa) had the most promising potential in producing AgNPs of 30±6 nm, with narrow size distribution and high crystallinity. The antimicrobial activities of these AgNPs conducted on E. coli cells were found to be superior in comparison to poly(vinylpyrrolidone)-capped AgNPs synthesized using common chemical method. Additionally, the AgNPs obtained possess excellent catalytic performance in the reduction of 4-nitrophenol to 4-aminophenol. We compared the phytochemical and FTIR spectral analyses of the herb extract before and after synthesis, in order to elucidate the phytochemicals responsible for the reduction of Ag ions and the capping of the AgNPs produced.

摘要

银纳米粒子(AgNPs)由于其抗菌和催化特性,在各种生物医学和环境应用中受到广泛关注。我们在这里提出了一种利用中药的绿色简单的 AgNPs 合成方法。对 20 种水提草药提取物的筛选表明,地黄(地黄)在产生 30±6nm 的 AgNPs 方面具有最有前途的潜力,其尺寸分布较窄且结晶度较高。与使用常见化学方法合成的聚乙烯吡咯烷酮(PVP)包覆的 AgNPs 相比,这些 AgNPs 对大肠杆菌细胞的抗菌活性更高。此外,所得到的 AgNPs 在还原 4-硝基苯酚为 4-氨基酚方面具有优异的催化性能。我们比较了合成前后草药提取物的植物化学和傅里叶变换红外光谱分析,以阐明负责还原 Ag 离子和包覆生成的 AgNPs 的植物化学物质。

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