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Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
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Reconstitution of S. cerevisiae RNA Exosome Complexes Using Recombinantly Expressed Proteins.
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Structure and regulation of the nuclear exosome targeting complex guides RNA substrates to the exosome.
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SnapShot: The RNA Exosome.
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Structural basis for MTR4-ZCCHC8 interactions that stimulate the MTR4 helicase in the nuclear exosome-targeting complex.
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Reconstitution of the Human Nuclear RNA Exosome.
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Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex.
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IDH1-dependent m6A methylation defines transcriptomic heterogeneity in glioma.
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Cytoplasmic mRNA decay and quality control machineries in eukaryotes.
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The competitive landscape of the dsRNA world.
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Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly.
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本文引用的文献

2
A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome.
Cell Rep. 2020 Feb 18;30(7):2387-2401.e5. doi: 10.1016/j.celrep.2020.01.068.
3
The Nuclear RNA Exosome and Its Cofactors.
Adv Exp Med Biol. 2019;1203:113-132. doi: 10.1007/978-3-030-31434-7_4.
4
The RNA Exosome and Human Disease.
Methods Mol Biol. 2020;2062:3-33. doi: 10.1007/978-1-4939-9822-7_1.
5
SnapShot: The RNA Exosome.
Cell. 2019 Sep 19;179(1):282-282.e1. doi: 10.1016/j.cell.2019.09.005.
6
, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation.
Genes Dev. 2019 Oct 1;33(19-20):1381-1396. doi: 10.1101/gad.326785.119. Epub 2019 Sep 5.
8
Towards a mechanistic understanding of cellular processes by cryoEM.
Curr Opin Struct Biol. 2019 Oct;58:149-158. doi: 10.1016/j.sbi.2019.06.008. Epub 2019 Jul 23.
9
NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction.
Genes Dev. 2019 May 1;33(9-10):536-549. doi: 10.1101/gad.322602.118. Epub 2019 Mar 6.

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