Smith K, Beighton D
Royal College of Surgeons, Dental Research Unit, Downe, Kent, England, U.K.
Arch Oral Biol. 1987;32(7):473-6. doi: 10.1016/s0003-9969(87)80007-9.
Thirteen peptidase substrates were hydrolysed by this plaque. After fasting the monkeys for 24 h, the rates of hydrolysis of N-leucyl-, N-alanyl-, N-isoleucyl- and N-tyrosyl-2-naphthylamines, glycyl-L-proline 4-nitroanilide, N alpha-benzoyl-DL-arginine-2-naphthylamine and L-leucyglycine were significantly increased. Changes in these peptidase activities may serve to enhance the mobilization of amino acids and peptides, and they may explain why the growth rates of dental-plaque bacteria in vivo are generally unaffected by the availability of the host's diet.
这种菌斑可水解13种肽酶底物。在使猴子禁食24小时后，N-亮氨酰-、N-丙氨酰-、N-异亮氨酰-和N-酪氨酰-2-萘胺、甘氨酰-L-脯氨酸4-硝基苯胺、Nα-苯甲酰-DL-精氨酸-2-萘胺和L-亮氨酰甘氨酸的水解速率显著增加。这些肽酶活性的变化可能有助于增强氨基酸和肽的动员，并且可以解释为什么体内牙菌斑细菌的生长速率通常不受宿主饮食供应情况的影响。
