South London and Maudsley NHS Foundation Trust, London, UK.
Addictions Department, King's College London Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Psychol Med. 2022 Jul;52(9):1691-1697. doi: 10.1017/S0033291720003451. Epub 2020 Nov 5.
Substance use and psychiatric illness, particularly psychotic disorders, contribute to violence in emergency healthcare settings. However, there is limited research regarding the relationship between specific substances, psychotic symptoms and violent behaviour in such settings. We investigated the interaction between recent cannabinoid and stimulant use, and acute psychotic symptoms, in relation to violent behaviour in a British emergency healthcare setting.
We used electronic medical records from detentions of 1089 individuals under Section 136 of the UK Mental Health Act (1983 amended 2007), an emergency police power used to detain people for 24-36 h for psychiatric assessment. The relationship between recent cannabinoids and/or stimulant use, psychotic symptoms, and violent behaviour, was estimated using logistic regression.
There was evidence of recent alcohol or drug use in 64.5% of detentions. Violent incidents occurred in 12.6% of detentions. Psychotic symptoms increased the odds of violence by 4.0 [95% confidence intervals (CI) 2.2-7.4; < 0.0001]. Cannabinoid use combined with psychotic symptoms increased the odds of violence further [odds ratios (OR) 7.1, 95% CI 3.7-13.6; < 0.0001]. Recent use of cannabinoids with stimulants but without psychotic symptoms was also associated with increased odds of violence (OR 3.3, 95% CI 1.4-7.9; < 0.0001).
In the emergency setting, patients who have recently used cannabinoids and exhibit psychotic symptoms are at higher risk of violent behaviour. Those who have used both stimulants and cannabinoids without psychotic symptoms may also be at increased risk. De-escalation protocols in emergency healthcare settings should account explicitly for substance use.
物质使用和精神疾病,尤其是精神病性障碍,导致了急诊医疗环境中的暴力行为。然而,关于特定物质、精神病症状与这种环境中的暴力行为之间的关系,相关研究有限。我们调查了英国急诊医疗环境中近期大麻素和兴奋剂使用情况与急性精神病症状与暴力行为之间的相互作用。
我们使用了英国 1983 年(经 2007 年修订)《精神卫生法》第 136 条规定下拘留的 1089 人的电子病历,这是一种紧急警察权力,用于将人们拘留 24-36 小时进行精神病评估。使用逻辑回归估计了近期大麻素和/或兴奋剂使用、精神病症状与暴力行为之间的关系。
在拘留中,有 64.5%的人有近期酒精或药物使用的证据。12.6%的拘留中发生了暴力事件。精神病症状使暴力发生的几率增加了 4.0 倍(95%置信区间[CI] 2.2-7.4;<0.0001)。大麻素使用合并精神病症状使暴力发生的几率进一步增加[比值比(OR)7.1,95%CI 3.7-13.6;<0.0001]。近期使用大麻素和兴奋剂但没有精神病症状也与暴力发生的几率增加有关(OR 3.3,95%CI 1.4-7.9;<0.0001)。
在急诊环境中,近期使用大麻素且表现出精神病症状的患者暴力行为的风险更高。那些既使用了兴奋剂又使用了大麻素但没有精神病症状的人也可能面临更高的风险。急诊医疗环境中的降级协议应明确考虑物质使用情况。