Sepat Poonam, Wasnik Sandhya
Department of Physiotherapy, All India Institute of Physical Medicine and Rehabilitation, India.
Associate Professor, Department of Physiotherapy, All India Institute of Physical Medicine and Rehabilitation, Mumbai, 400034, India.
Heliyon. 2020 Oct 27;6(10):e05318. doi: 10.1016/j.heliyon.2020.e05318. eCollection 2020 Oct.
The study intends to find out the effect of Type 2 diabetes on the sensory nerve of the upper extremity.
This research includes 100 subjects, both male and female, within the age group of 40-80 years. The subjects were divided into two groups, A and B. Where Group A includes 50 subjects which diagnosed type 2 diabetic mellitus. Furthermore, Group B holds 50 normal healthy subjects investigated and normal healthy subjects without diabetes mellitus Written consent was obtained from the subjects who were ready to be part of this study. Orthodromic sensory nerve conduction studies of median, ulnar, and radial nerve were assessed by using EMG diagnostic device for bilateral upper extremities in both groups. The sensory nerve conduction study included nerve conduction velocity (m/s), latency (ms), and amplitude (μV). The data analyzed using paired 't' test within the group and unpaired 't' test between two groups, using computational statistical software Graph Pad Prism. 'p' value < 0.05 was considered to be statistically significant.
The sensory nerve amplitude of all three nerves reduced the velocity of the median & ulnar nerve was reduced and prolonged latency of ulnar nerve in type 2 diabetics as compared to the Non-diabetics group.
This study concluded that the type 2 diabetics group has severe sensory nerve affections of the median and ulnar nerve. The therapist should examine the upper extremity of all diabetic subjects, and hand care should be taught to the patients to prevent further complications of diabetic peripheral neuropathy.
本研究旨在探究2型糖尿病对上肢感觉神经的影响。
本研究纳入了100名年龄在40 - 80岁之间的男女受试者。将受试者分为A、B两组。其中A组有50名被诊断为2型糖尿病的受试者。此外,B组有50名健康正常受试者。已获得愿意参与本研究的受试者的书面同意。使用肌电图诊断设备对两组双侧上肢的正中神经、尺神经和桡神经进行顺向感觉神经传导研究。感觉神经传导研究包括神经传导速度(米/秒)、潜伏期(毫秒)和波幅(微伏)。使用计算统计软件Graph Pad Prism对组内数据采用配对“t”检验,对两组之间的数据采用非配对“t”检验。“p”值<0.05被认为具有统计学意义。
与非糖尿病组相比,2型糖尿病患者所有三条神经的感觉神经波幅降低,正中神经和尺神经的速度降低,尺神经潜伏期延长。
本研究得出结论,2型糖尿病患者组存在正中神经和尺神经严重的感觉神经病变。治疗师应检查所有糖尿病患者的上肢,并向患者传授手部护理知识,以预防糖尿病周围神经病变的进一步并发症。