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The 5q- abnormality.

作者信息

Nimer S D, Golde D W

机构信息

Division of Hematology-Oncology, UCLA School of Medicine.

出版信息

Blood. 1987 Dec;70(6):1705-12.

PMID:3315038
Abstract
摘要

相似文献

1
The 5q- abnormality.5号染色体长臂缺失异常
Blood. 1987 Dec;70(6):1705-12.
2
5q-: pathogenetic importance of the common deleted region and clinical consequences of the entire deleted segment.5号染色体长臂缺失：常见缺失区域的致病重要性及整个缺失片段的临床后果。
Anticancer Res. 1993 Sep-Oct;13(5C):1913-6.
3
Different boundaries characterize isolated and non-isolated 5q deletions in myelodysplastic syndromes and acute myeloid leukemias.不同的边界特征区分了骨髓增生异常综合征和急性髓系白血病中孤立性和非孤立性5q缺失。
Haematologica. 2012 May;97(5):792-4. doi: 10.3324/haematol.2011.060111. Epub 2012 Feb 13.
4
Involvement of both chromosomes 5 in a patient with leukemia secondary to myelodysplastic syndrome.
Cancer Genet Cytogenet. 1990 Sep;48(2):279-80. doi: 10.1016/0165-4608(90)90133-u.
5
Myelodysplastic syndrome with concomitant del(5q) and JAK2 V617F mutation transformed to acute myeloid leukemia with an additional chromosomal abnormality after a long-term treatment with lenalidomide.伴有del(5q)和JAK2 V617F突变的骨髓增生异常综合征在长期使用来那度胺治疗后转化为急性髓系白血病，并伴有额外的染色体异常。
Leuk Lymphoma. 2017 Oct;58(10):2511-2513. doi: 10.1080/10428194.2017.1295146. Epub 2017 Feb 28.
6
Any role for the nucleophosmin (NPM1) gene in myelodysplastic syndromes and acute myeloid leukemia with chromosome 5 abnormalities?
Leuk Lymphoma. 2007 Nov;48(11):2093-5. doi: 10.1080/10428190701684534.
7
Translocation (8;21)(q22;q22) and the myelodysplastic syndrome.
Leuk Res. 1995 Sep;19(9):675-7. doi: 10.1016/0145-2126(95)00055-s.
8
Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia.5号染色体长臂缺失的骨髓增生异常综合征转化为急性髓系白血病时的全外显子组测序
Leukemia. 2014 May;28(5):1148-51. doi: 10.1038/leu.2013.381. Epub 2013 Dec 24.
9
[Aberrations of chromosome 5 in myeloid malignancies with complex chromosome abnormalities].
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2008 Dec;16(6):1257-60.
10
Does monosomy 5 really exist in myelodysplastic syndromes and acute myeloid leukemia?真的存在骨髓增生异常综合征和急性髓系白血病的单体 5 吗？
Leuk Res. 2010 Sep;34(9):1242-5. doi: 10.1016/j.leukres.2010.03.022. Epub 2010 Apr 1.

引用本文的文献

1
Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.5q-综合征发病机制中的重要基因及其与核糖体应激和固有免疫系统通路的联系。
Leuk Res Treatment. 2012;2012:179402. doi: 10.1155/2012/179402. Epub 2012 Feb 13.
2
The 5q- syndrome: biology and treatment.5q- 综合征：生物学与治疗。
Curr Treat Options Oncol. 2011 Dec;12(4):354-68. doi: 10.1007/s11864-011-0165-1.
3
NPM1 gene deletions in myelodysplastic syndromes with 5q- and complex karyotype.伴有5q-和复杂核型的骨髓增生异常综合征中的NPM1基因缺失
Haematologica. 2011 May;96(5):784-5. doi: 10.3324/haematol.2010.038620. Epub 2011 Mar 10.
4
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy.多面 Polo 样激酶：癌症治疗的药物靶点和反靶点。
Nat Rev Drug Discov. 2010 Aug;9(8):643-60. doi: 10.1038/nrd3184.
5
Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.与晚期髓系恶性肿瘤相关的CTNNA1的渐进性染色质抑制和启动子甲基化。
Cancer Res. 2009 Nov 1;69(21):8482-90. doi: 10.1158/0008-5472.CAN-09-1153. Epub 2009 Oct 13.
6
The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: how does it relate to the original lenalidomide experience in MDS?骨髓增生异常综合征合并5号染色体异常患者的异质性预后：它与来那度胺在骨髓增生异常综合征中的原始应用经验有何关联？
Cancer. 2009 Nov 15;115(22):5202-9. doi: 10.1002/cncr.24575.
7
Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies.斑马鱼14号连锁群与人类染色体5在髓系恶性肿瘤中频繁缺失区域的进化保守性。
Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6136-41. doi: 10.1073/pnas.072560099.
8
Critical evaluation of the World Health Organization classification of myelodysplasia and acute myeloid leukemia.对世界卫生组织骨髓增生异常综合征和急性髓系白血病分类的批判性评估。
Curr Oncol Rep. 2000 Mar;2(2):140-3. doi: 10.1007/s11912-000-0085-x.
9
Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.恶性髓系疾病中5号染色体最小常见缺失区域的分子界定至1 - 1.5兆碱基，并构建基于P1人工染色体的物理图谱。
Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6948-53. doi: 10.1073/pnas.94.13.6948.
10
The process of leukemogenesis.白血病发生的过程。
Environ Health Perspect. 1996 Dec;104 Suppl 6(Suppl 6):1239-46. doi: 10.1289/ehp.961041239.