Maneetong Photcharaphan, Srisang Chutikan, Sunanta Naritsara, Muchalintamolee Praeploy, Pearodwong Pachara, Suwimonteerabutr Junpen, De Rensis Fabio, Tummaruk Padet
Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
School of Agricultural Resources, Chulalongkorn University, Bangkok 10330, Thailand.
Anim Biosci. 2021 May;34(5):833-843. doi: 10.5713/ajas.20.0187. Epub 2020 Oct 13.
Current study was conducted to determine the effect of postpartum prostaglandin F2α (PGF2α) administration on colostrum and milk yield, colostrum immunoglobulin G (IgG) and piglet growth performance.
In total, 36 sows were included in the experiment. The sows were classified into two groups: i) control (n = 11) and ii) PGF2α (n = 25). Sows in the PGF2α group received 10 mg of PGF2α within an hour after farrowing. The body weight of piglets was measured at 0 and 24 h after birth to estimate colostrum consumption. Colostrum was collected at 1 and 24 h after farrowing to determine IgG concentrations. For milk yield study, the remaining sows in the PGF2α group (n = 23) were divided into two subgroups: i) single PGF2α (n = 12) and ii) multiple PGF2α (n = 11). In the multiple PGF2α, the sows received repeated doses of PGF2α at seven and 14 days postpartum. The piglets' body weight was measured at 0, 1, 5, and 20 days of age. The milk yield of the sows was calculated.
Colostrum yield of sows averaged 5.62±2.25 kg. Sows treated with PGF2α postpartum had a higher colostrum yield than control (7.01 and 5.12 kg, p<0.05). The concentration of IgG in colostrum at 24 h in the PGF2α group was higher than the control (31.6 and 17.4 g/L, p<0.05). For primiparous sows, milk yield was highest in the sows treated with multiple doses of PGF2α during lactation and lowest in control sows (10.25 and 7.61 kg, p<0.05). Colostrum intake was higher in the treatment than the control groups (+56.7 g, p<0.05). Primiparous sows treated with multiple doses of PGF2α had a higher litter weight than controls (p<0.01).
Postpartum treatment with PGF2α improved colostrum yield and IgG in multiparous sows and increased colostrum intake of piglets. Multiple administration of PGF2α improved the milk yield and increased litter weight of piglets in primiparous sows.
本研究旨在确定产后注射前列腺素F2α（PGF2α）对初乳和乳汁产量、初乳免疫球蛋白G（IgG）以及仔猪生长性能的影响。
本实验共纳入36头母猪。母猪被分为两组：i）对照组（n = 11）和ii）PGF2α组（n = 25）。PGF2α组的母猪在分娩后1小时内接受10毫克PGF2α。在出生后0小时和24小时测量仔猪体重，以估计初乳摄入量。在分娩后1小时和24小时采集初乳，以测定IgG浓度。为了研究乳汁产量，PGF2α组中剩余的母猪（n = 23）被分为两个亚组：i）单次PGF2α组（n = 12）和ii）多次PGF2α组（n = 11）。在多次PGF2α组中，母猪在产后7天和14天接受重复剂量的PGF2α。在仔猪0日龄、1日龄、5日龄和20日龄时测量其体重。计算母猪的乳汁产量。
母猪的初乳产量平均为5.62±2.25千克。产后接受PGF2α治疗的母猪初乳产量高于对照组（分别为7.01千克和5.12千克，p<0.05）。PGF2α组在24小时时初乳中IgG的浓度高于对照组（分别为31.6克/升和17.4克/升，p<0.05）。对于初产母猪，哺乳期接受多次剂量PGF2α治疗的母猪乳汁产量最高，对照组母猪最低（分别为10.25千克和7.61千克，p<0.05）。治疗组的初乳摄入量高于对照组（多56.7克，p<0.05）。接受多次剂量PGF2α治疗的初产母猪的仔猪窝重高于对照组（p<0.01）。
产后用PGF2α治疗可提高经产母猪的初乳产量和IgG含量，并增加仔猪的初乳摄入量。多次施用PGF2α可提高初产母猪的乳汁产量并增加仔猪窝重。
