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富含甲基丁香酚的摩洛哥 Zantaz 蜂蜜的理化特性及其抗增殖和抗氧化活性。

Physicochemical characteristics and antiproliferative and antioxidant activities of Moroccan Zantaz honey rich in methyl syringate.

机构信息

Laboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of Life (SNAMOPEQ), University of Sidi Mohamed Ben Abdellah, Fez 30 000, Morocco; Instituto de la Grasa (C.S.I.C.), Universidad Pablo de Olavide, Edificio 46, Carretera de Utrera, km 1, 41013-Sevilla, Spain.

Laboratory of Natural Substances, Pharmacology, Environment, Modeling, Health and Quality of Life (SNAMOPEQ), University of Sidi Mohamed Ben Abdellah, Fez 30 000, Morocco.

出版信息

Food Chem. 2021 Mar 1;339:128098. doi: 10.1016/j.foodchem.2020.128098. Epub 2020 Sep 16.

DOI:10.1016/j.foodchem.2020.128098
PMID:33152883
Abstract

Zantaz honey is a monofloral variety produced from the melliferous plant Bupleurum spinosum (Apiaceae), a shrub that grows mainly in the Atlas Moroccan Mountains. Determination of the polyphenol composition revealed that methyl syringate accounts for more than 50% of total polyphenols, which represents a very useful parameter for the characterization of this monofloral honey. Epicatechin, syringic acid and catechin are also abundant. Caco-2 and THP-1 cells were used for determination of antioxidant and antiproliferative activities in Zantaz honey, respectively. All six commercial samples that were used for these studies exhibited antioxidant activity and inhibited cell proliferation. Interestingly, these activities had a positive correlation mainly with the content in methyl syringate and gallic acid. The recognition of health promoting activities in Zantaz honey should increase its commercial value, which would have a positive economic impact on the poor rural communities of Morocco where it is produced.

摘要

赞特兹蜂蜜是一种单花蜜品种,由多刺菘蓝(伞形科)这种蜜源植物生产,多刺菘蓝主要生长在摩洛哥阿特拉斯山脉。多酚成分的测定显示,甲基丁香酸盐占总多酚的 50%以上,这是表征这种单花蜜的一个非常有用的参数。表儿茶素、丁香酸和儿茶素也很丰富。Caco-2 和 THP-1 细胞分别用于测定赞特兹蜂蜜的抗氧化和抗增殖活性。在这些研究中使用的所有六种商业样本均表现出抗氧化活性并抑制细胞增殖。有趣的是,这些活性主要与甲基丁香酸盐和没食子酸的含量呈正相关。赞特兹蜂蜜的促进健康活动的认可将提高其商业价值,这将对其产地摩洛哥贫困的农村社区产生积极的经济影响。

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