Berkman Amy M, Robert Rhonda S, Roth Michael, Askins Martha A
Duke University School of Medicine, USA.
The University of Texas MD Anderson Cancer Center, USA.
J Health Psychol. 2022 Mar;27(4):990-1005. doi: 10.1177/1359105320971706. Epub 2020 Nov 6.
The majority of childhood cancer patients survive well into adulthood, but remain at risk for psychological late effects that can impact overall health and quality of life. The current narrative review summarizes the literature on psychological late effects, including anxiety, depression, psychological distress, post-traumatic stress disorder, suicidality, psychoactive medication use, and post-traumatic growth in survivors of childhood cancers. While results were mixed, many studies demonstrated that psychological symptoms occurred at levels higher than would be expected in the general population. Treatment, environmental, and behavioral risk factors, as well as symptom onset and trajectory merit further investigation.
大多数儿童癌症患者都能顺利活到成年，但仍面临心理后期效应的风险，这些效应可能会影响整体健康和生活质量。本叙述性综述总结了关于心理后期效应的文献，包括焦虑、抑郁、心理困扰、创伤后应激障碍、自杀倾向、精神活性药物使用以及儿童癌症幸存者的创伤后成长。虽然结果不一，但许多研究表明，心理症状的出现水平高于一般人群的预期。治疗、环境和行为风险因素，以及症状的发作和发展轨迹值得进一步研究。
