In silico Research Laboratory, Eminent Biosciences, Indore-452 010, Madhya Pradesh, India
Bioinformatics Research Laboratory, LeGene Biosciences Pvt Ltd, Indore-452010, Madhya Pradesh, India
Curr Top Med Chem. 2020;20(24):2119-2125. doi: 10.2174/156802662023201001094634.
Multidrug resistance in microbes poses a major health crisis and demands for the discovery of novel antimicrobial agents. The recent pandemic of SARS-CoV-2 has raised a public health emergency in almost all the countries of the world. Unlike viruses, a bacterium plays a significant role in various environmental issues such as bioremediation. Furthermore, biosurfactants produced by various bacterial species have an edge over traditionally produced chemical surfactants for its biodegradability, low toxicity and better interfacial activity with various applications in agriculture and industry. This special issue focuses on the global perspective of drug discovery for various antimicrobial, antiviral, and antifungal agents for infectious diseases. The issue also emphasizes the ongoing developments and the role of microbes in environmental remediation. We wish the articles published in this issue will enhance the current understanding in microbiology among the readers, and serve as the "seed of an idea" for drug development for ongoing COVID-19 pandemic.
微生物的多药耐药性对全球健康构成重大威胁，因此需要开发新型抗菌药物。最近的 SARS-CoV-2 大流行在世界几乎所有国家都引发了公共卫生紧急事件。与病毒不同，细菌在生物修复等各种环境问题中发挥着重要作用。此外，各种细菌产生的生物表面活性剂在生物降解性、低毒性和与农业和工业中各种应用的更好界面活性方面优于传统生产的化学表面活性剂。本特刊重点关注针对各种抗菌、抗病毒和抗真菌药物的全球药物发现视角，以应对传染病。本特刊还强调了微生物在环境修复方面的最新进展和作用。我们希望本期发表的文章能够提高读者对微生物学的认识，并为应对当前的 COVID-19 大流行提供药物开发的“思路”。
