Department of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Cochin, Kerala, India.
Cholera and Biofilm Research Laboratory, Rajiv Gandhi Center for Biotechnology, Trivandrum, Kerala, India.
Indian J Med Microbiol. 2020 Jul-Dec;38(3 & 4):489-491. doi: 10.4103/ijmm.IJMM_20_283.
Vibrios have been identified to cause extra-intestinal complications apart from the occasional cholera-like diarrhoeal outbreaks. The non-O1/O139 Vibrio cholerae strains are ubiquitous in environmental water bodies and hence pose a threat to people even without obvious risk factors. We describe a case of sepsis in a child with spinal dysraphism caused by a V. cholerae O9 strain belonging to a novel sequence type (ST520). The present case highlights the need of considering V. cholerae non-O1/O139 as one of the pathogens while dealing with sepsis cases, and also, the study expounds the importance of proper characterisation of the pathogen for an effective treatment.
除了偶尔发生霍乱样腹泻暴发外,弧菌已被确定可引起肠道外并发症。非 O1/O139 霍乱弧菌菌株在环境水体中无处不在,因此即使没有明显的危险因素,也对人们构成威胁。我们描述了一例由属于新型序列型(ST520)的 O9 霍乱弧菌引起的脊髓发育不良儿童败血症病例。本病例强调了在处理败血症病例时需要将非 O1/O139 霍乱弧菌视为病原体之一,同时研究还阐述了对病原体进行适当特征描述以进行有效治疗的重要性。